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- NCIT_C66181 IAO_0000115 "A synthetic topical glucocorticoid receptor (GR) agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Upon administration, mometasone binds to cytoplasmic GRs and subsequently activates GR-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, mometasone appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2." @default.
- NCIT_C66181 NCIT_A5 NCIT_C29268 @default.
- NCIT_C66181 NCIT_NHC0 "C66181" @default.
- NCIT_C66181 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66181 NCIT_P108 "Mometasone" @default.
- NCIT_C66181 NCIT_P207 "C0360564" @default.
- NCIT_C66181 NCIT_P210 "105102-22-5" @default.
- NCIT_C66181 NCIT_P319 "8HR4QJ6DW8" @default.
- NCIT_C66181 NCIT_P322 "FDA" @default.
- NCIT_C66181 NCIT_P325 "A drug that is used in a cream to treat certain skin conditions and in a nasal spray to treat sinus problems caused by allergies. It is being studied as a way to treat inflammation of the skin caused by radiation therapy. Mometasone is a type of corticosteroid." @default.
- NCIT_C66181 NCIT_P350 "C22H28Cl2O4" @default.
- NCIT_C66181 NCIT_P366 "Mometasone" @default.
- NCIT_C66181 NCIT_P368 "CHEBI:6970" @default.
- NCIT_C66181 normalizedInformationContent "100" @default.
- NCIT_C66181 referenceCount "1" @default.
- NCIT_C66181 hasExactSynonym "MOMETASONE" @default.
- NCIT_C66181 hasExactSynonym "Mometasone" @default.
- NCIT_C66181 hasExactSynonym "mometasone" @default.
- NCIT_C66181 inSubset NCIT_C173381 @default.
- NCIT_C66181 inSubset NCIT_C173383 @default.
- NCIT_C66181 inSubset NCIT_C63923 @default.
- NCIT_C66181 type Class @default.
- NCIT_C66181 isDefinedBy ncit.owl @default.
- NCIT_C66181 label "Mometasone" @default.
- NCIT_C66181 subClassOf NCIT_C147908 @default.
- NCIT_C66181 subClassOf NCIT_C1636 @default.
- NCIT_C66181 subClassOf NCIT_C1908 @default.
- NCIT_C66181 subClassOf NCIT_C1909 @default.
- NCIT_C66181 subClassOf NCIT_C211 @default.
- NCIT_C66181 subClassOf NCIT_C2364 @default.
- NCIT_C66181 subClassOf NCIT_C308 @default.
- NCIT_C66181 subClassOf NCIT_C548 @default.
- NCIT_C66181 subClassOf NCIT_C574 @default.
- NCIT_C66181 subClassOf NCIT_C66181 @default.