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- NCIT_C66215 IAO_0000115 "The sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase (IMPDH) which is needed for guanine monophosphate synthesis and stops the proliferation of B and T lymphocytes. Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity." @default.
- NCIT_C66215 NCIT_A6 NCIT_C673 @default.
- NCIT_C66215 NCIT_NHC0 "C66215" @default.
- NCIT_C66215 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66215 NCIT_P108 "Mycophenolate Sodium" @default.
- NCIT_C66215 NCIT_P175 "116072" @default.
- NCIT_C66215 NCIT_P207 "C1337395" @default.
- NCIT_C66215 NCIT_P210 "37415-62-6" @default.
- NCIT_C66215 NCIT_P319 "WX877SQI1G" @default.
- NCIT_C66215 NCIT_P322 "FDA" @default.
- NCIT_C66215 NCIT_P350 "C17H19O6.Na" @default.
- NCIT_C66215 NCIT_P366 "Mycophenolate_Sodium" @default.
- NCIT_C66215 normalizedInformationContent "100" @default.
- NCIT_C66215 referenceCount "1" @default.
- NCIT_C66215 hasExactSynonym "4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, monosodium salt, (4E)-" @default.
- NCIT_C66215 hasExactSynonym "ERL 080" @default.
- NCIT_C66215 hasExactSynonym "ERL 080A" @default.
- NCIT_C66215 hasExactSynonym "MYCOPHENOLATE SODIUM" @default.
- NCIT_C66215 hasExactSynonym "Mycophenolate Sodium" @default.
- NCIT_C66215 hasExactSynonym "Socium Mycophenolate" @default.
- NCIT_C66215 inSubset NCIT_C63923 @default.
- NCIT_C66215 type Class @default.
- NCIT_C66215 isDefinedBy ncit.owl @default.
- NCIT_C66215 label "Mycophenolate Sodium" @default.
- NCIT_C66215 subClassOf NCIT_C1908 @default.
- NCIT_C66215 subClassOf NCIT_C1909 @default.
- NCIT_C66215 subClassOf NCIT_C2087 @default.
- NCIT_C66215 subClassOf NCIT_C308 @default.
- NCIT_C66215 subClassOf NCIT_C471 @default.
- NCIT_C66215 subClassOf NCIT_C574 @default.
- NCIT_C66215 subClassOf NCIT_C66215 @default.