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- NCIT_C66253 IAO_0000115 "A synthetic imidazole derivative and angiotensin II receptor antagonist with antihypertensive activity. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor subtype in vascular smooth muscle and adrenal gland, thereby competing with angiotensin II for binding to the AT1 receptor. This prevents angiotensin II-induced vasoconstriction and interferes with angiotensin II-mediated aldosterone secretion, thereby decreasing aldosterone production and preventing aldosterone-stimulated sodium retention and potassium excretion." @default.
- NCIT_C66253 NCIT_A5 NCIT_C47640 @default.
- NCIT_C66253 NCIT_NHC0 "C66253" @default.
- NCIT_C66253 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66253 NCIT_P108 "Olmesartan" @default.
- NCIT_C66253 NCIT_P207 "C1098320" @default.
- NCIT_C66253 NCIT_P210 "144689-24-7" @default.
- NCIT_C66253 NCIT_P319 "8W1IQP3U10" @default.
- NCIT_C66253 NCIT_P322 "FDA" @default.
- NCIT_C66253 NCIT_P350 "C24H26N6O3" @default.
- NCIT_C66253 NCIT_P366 "Olmesartan" @default.
- NCIT_C66253 NCIT_P368 "CHEBI:48416" @default.
- NCIT_C66253 normalizedInformationContent "100" @default.
- NCIT_C66253 referenceCount "1" @default.
- NCIT_C66253 hasExactSynonym "OLMESARTAN" @default.
- NCIT_C66253 hasExactSynonym "Olmesartan" @default.
- NCIT_C66253 inSubset NCIT_C173381 @default.
- NCIT_C66253 inSubset NCIT_C173383 @default.
- NCIT_C66253 inSubset NCIT_C63923 @default.
- NCIT_C66253 type Class @default.
- NCIT_C66253 isDefinedBy ncit.owl @default.
- NCIT_C66253 label "Olmesartan" @default.
- NCIT_C66253 subClassOf NCIT_C1908 @default.
- NCIT_C66253 subClassOf NCIT_C1909 @default.
- NCIT_C66253 subClassOf NCIT_C270 @default.
- NCIT_C66253 subClassOf NCIT_C66253 @default.
- NCIT_C66253 subClassOf NCIT_C66930 @default.
- NCIT_C66253 subClassOf NCIT_C78274 @default.