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- NCIT_C66334 IAO_0000115 "A pyrimidinone derivative with anti-allergic activity. Pemirolast blocks the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in the allergic process. Pemirolast also prevents inflammatory mediator release from eosinophils." @default.
- NCIT_C66334 NCIT_A5 NCIT_C47654 @default.
- NCIT_C66334 NCIT_NHC0 "C66334" @default.
- NCIT_C66334 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66334 NCIT_P108 "Pemirolast" @default.
- NCIT_C66334 NCIT_P207 "C0053881" @default.
- NCIT_C66334 NCIT_P210 "69372-19-6" @default.
- NCIT_C66334 NCIT_P319 "2C09NV773M" @default.
- NCIT_C66334 NCIT_P322 "FDA" @default.
- NCIT_C66334 NCIT_P350 "C10H8N6O" @default.
- NCIT_C66334 NCIT_P366 "Pemirolast" @default.
- NCIT_C66334 normalizedInformationContent "100" @default.
- NCIT_C66334 referenceCount "1" @default.
- NCIT_C66334 hasExactSynonym "4H-Pyrido(1,2-a)Pyrimidin-4-One, 9-Methyl-3-(1H-Tetrazol-5-yl)-" @default.
- NCIT_C66334 hasExactSynonym "PEMIROLAST" @default.
- NCIT_C66334 hasExactSynonym "Pemirolast" @default.
- NCIT_C66334 inSubset NCIT_C63923 @default.
- NCIT_C66334 type Class @default.
- NCIT_C66334 isDefinedBy ncit.owl @default.
- NCIT_C66334 label "Pemirolast" @default.
- NCIT_C66334 subClassOf NCIT_C1908 @default.
- NCIT_C66334 subClassOf NCIT_C1909 @default.
- NCIT_C66334 subClassOf NCIT_C29712 @default.
- NCIT_C66334 subClassOf NCIT_C29714 @default.
- NCIT_C66334 subClassOf NCIT_C66334 @default.
- NCIT_C66334 subClassOf NCIT_C78273 @default.