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- NCIT_C66336 IAO_0000115 "A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, penbutolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels." @default.
- NCIT_C66336 NCIT_A5 NCIT_C61882 @default.
- NCIT_C66336 NCIT_NHC0 "C66336" @default.
- NCIT_C66336 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66336 NCIT_P108 "Penbutolol" @default.
- NCIT_C66336 NCIT_P207 "C0030812" @default.
- NCIT_C66336 NCIT_P210 "38363-40-5" @default.
- NCIT_C66336 NCIT_P319 "78W62V43DY" @default.
- NCIT_C66336 NCIT_P322 "FDA" @default.
- NCIT_C66336 NCIT_P350 "C18H29NO2" @default.
- NCIT_C66336 NCIT_P366 "Penbutolol" @default.
- NCIT_C66336 NCIT_P368 "CHEBI:7954" @default.
- NCIT_C66336 normalizedInformationContent "100" @default.
- NCIT_C66336 referenceCount "1" @default.
- NCIT_C66336 hasExactSynonym "PENBUTOLOL" @default.
- NCIT_C66336 hasExactSynonym "Penbutolol" @default.
- NCIT_C66336 inSubset NCIT_C63923 @default.
- NCIT_C66336 type Class @default.
- NCIT_C66336 isDefinedBy ncit.owl @default.
- NCIT_C66336 label "Penbutolol" @default.
- NCIT_C66336 subClassOf NCIT_C1908 @default.
- NCIT_C66336 subClassOf NCIT_C1909 @default.
- NCIT_C66336 subClassOf NCIT_C29576 @default.
- NCIT_C66336 subClassOf NCIT_C29747 @default.
- NCIT_C66336 subClassOf NCIT_C66336 @default.
- NCIT_C66336 subClassOf NCIT_C72900 @default.
- NCIT_C66336 subClassOf NCIT_C78272 @default.