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- NCIT_C664 IAO_0000115 "A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production. (NCI04)" @default.
- NCIT_C664 NCIT_A32 NCIT_C1909 @default.
- NCIT_C664 NCIT_NHC0 "C664" @default.
- NCIT_C664 NCIT_P106 "Organic Chemical" @default.
- NCIT_C664 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C664 NCIT_P107 "Mitotane" @default.
- NCIT_C664 NCIT_P108 "Mitotane" @default.
- NCIT_C664 NCIT_P175 "38721" @default.
- NCIT_C664 NCIT_P207 "C0026256" @default.
- NCIT_C664 NCIT_P210 "53-19-0" @default.
- NCIT_C664 NCIT_P302 "Adrenocortical carcinoma" @default.
- NCIT_C664 NCIT_P319 "78E4J5IB5J" @default.
- NCIT_C664 NCIT_P322 "CTRP" @default.
- NCIT_C664 NCIT_P322 "FDA" @default.
- NCIT_C664 NCIT_P322 "GDC" @default.
- NCIT_C664 NCIT_P325 "An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing's disease)." @default.
- NCIT_C664 NCIT_P329 "39506" @default.
- NCIT_C664 NCIT_P330 "39506" @default.
- NCIT_C664 NCIT_P350 "C14H10Cl4" @default.
- NCIT_C664 NCIT_P366 "Mitotane" @default.
- NCIT_C664 NCIT_P375 "Mitotane" @default.
- NCIT_C664 NCIT_P399 "39506" @default.
- NCIT_C664 normalizedInformationContent "86.239998175184226" @default.
- NCIT_C664 referenceCount "8" @default.
- NCIT_C664 hasExactSynonym "(o,p)-DDD" @default.
- NCIT_C664 hasExactSynonym "1, 1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane" @default.
- NCIT_C664 hasExactSynonym "1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane" @default.
- NCIT_C664 hasExactSynonym "1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene" @default.
- NCIT_C664 hasExactSynonym "2, 2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane" @default.
- NCIT_C664 hasExactSynonym "2, 4'-Dichlorodiphenyldichloroethane" @default.
- NCIT_C664 hasExactSynonym "2,2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane" @default.
- NCIT_C664 hasExactSynonym "2,4'-Dichlorodiphenyldichloroethane" @default.
- NCIT_C664 hasExactSynonym "2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane" @default.
- NCIT_C664 hasExactSynonym "CB 313" @default.
- NCIT_C664 hasExactSynonym "CB-313" @default.
- NCIT_C664 hasExactSynonym "Chloditan" @default.
- NCIT_C664 hasExactSynonym "Chlodithane" @default.
- NCIT_C664 hasExactSynonym "DDD" @default.
- NCIT_C664 hasExactSynonym "Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-" @default.
- NCIT_C664 hasExactSynonym "Khloditan" @default.
- NCIT_C664 hasExactSynonym "Lisodren" @default.
- NCIT_C664 hasExactSynonym "Lysodren" @default.
- NCIT_C664 hasExactSynonym "MITOTANE" @default.
- NCIT_C664 hasExactSynonym "Mitotane" @default.
- NCIT_C664 hasExactSynonym "Mytotan" @default.
- NCIT_C664 hasExactSynonym "Ortho,para-DDD" @default.
- NCIT_C664 hasExactSynonym "WR-13045" @default.
- NCIT_C664 hasExactSynonym "mitotane" @default.
- NCIT_C664 hasExactSynonym "o,p' - DDD" @default.
- NCIT_C664 hasExactSynonym "o,p'-DDD" @default.
- NCIT_C664 inSubset NCIT_C116977 @default.
- NCIT_C664 inSubset NCIT_C116978 @default.
- NCIT_C664 inSubset NCIT_C128784 @default.
- NCIT_C664 inSubset NCIT_C157711 @default.
- NCIT_C664 inSubset NCIT_C157712 @default.
- NCIT_C664 inSubset NCIT_C176424 @default.
- NCIT_C664 inSubset NCIT_C177537 @default.
- NCIT_C664 inSubset NCIT_C63923 @default.
- NCIT_C664 type Class @default.
- NCIT_C664 isDefinedBy ncit.owl @default.
- NCIT_C664 label "Mitotane" @default.
- NCIT_C664 subClassOf NCIT_C147908 @default.
- NCIT_C664 subClassOf NCIT_C1908 @default.
- NCIT_C664 subClassOf NCIT_C1909 @default.
- NCIT_C664 subClassOf NCIT_C2355 @default.
- NCIT_C664 subClassOf NCIT_C547 @default.
- NCIT_C664 subClassOf NCIT_C664 @default.