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- NCIT_C66483 IAO_0000115 "A semisynthetic, acid stable, penicillin with antibacterial activity. Propicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis." @default.
- NCIT_C66483 NCIT_NHC0 "C66483" @default.
- NCIT_C66483 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66483 NCIT_P108 "Propicillin" @default.
- NCIT_C66483 NCIT_P207 "C0072176" @default.
- NCIT_C66483 NCIT_P210 "551-27-9" @default.
- NCIT_C66483 NCIT_P319 "8X1R260V33" @default.
- NCIT_C66483 NCIT_P322 "FDA" @default.
- NCIT_C66483 NCIT_P350 "C18H22N2O5S" @default.
- NCIT_C66483 NCIT_P366 "Propicillin" @default.
- NCIT_C66483 NCIT_P368 "CHEBI:52429" @default.
- NCIT_C66483 normalizedInformationContent "100" @default.
- NCIT_C66483 referenceCount "1" @default.
- NCIT_C66483 hasExactSynonym "PROPICILLIN" @default.
- NCIT_C66483 hasExactSynonym "Propicillin" @default.
- NCIT_C66483 inSubset NCIT_C63923 @default.
- NCIT_C66483 type Class @default.
- NCIT_C66483 isDefinedBy ncit.owl @default.
- NCIT_C66483 label "Propicillin" @default.
- NCIT_C66483 subClassOf NCIT_C1500 @default.
- NCIT_C66483 subClassOf NCIT_C1908 @default.
- NCIT_C66483 subClassOf NCIT_C1909 @default.
- NCIT_C66483 subClassOf NCIT_C254 @default.
- NCIT_C66483 subClassOf NCIT_C258 @default.
- NCIT_C66483 subClassOf NCIT_C260 @default.
- NCIT_C66483 subClassOf NCIT_C66483 @default.