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- NCIT_C66599 IAO_0000115 "The sodium salt form of thiopental, an ultrashort-acting barbituric acid derivative, with anesthetic activity. Thiopental binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses." @default.
- NCIT_C66599 NCIT_A6 NCIT_C72166 @default.
- NCIT_C66599 NCIT_NHC0 "C66599" @default.
- NCIT_C66599 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66599 NCIT_P108 "Thiopental Sodium" @default.
- NCIT_C66599 NCIT_P207 "C0936073" @default.
- NCIT_C66599 NCIT_P210 "71-73-8" @default.
- NCIT_C66599 NCIT_P319 "49Y44QZL70" @default.
- NCIT_C66599 NCIT_P322 "FDA" @default.
- NCIT_C66599 NCIT_P350 "C11H17N2O2S.Na" @default.
- NCIT_C66599 NCIT_P366 "Thiopental_Sodium" @default.
- NCIT_C66599 NCIT_P368 "CHEBI:9561" @default.
- NCIT_C66599 normalizedInformationContent "100" @default.
- NCIT_C66599 referenceCount "1" @default.
- NCIT_C66599 hasExactSynonym "4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, Monosodium Salt" @default.
- NCIT_C66599 hasExactSynonym "Pentothal" @default.
- NCIT_C66599 hasExactSynonym "Sodium Penthiobarbital" @default.
- NCIT_C66599 hasExactSynonym "Sodium Thiopental" @default.
- NCIT_C66599 hasExactSynonym "THIOPENTAL SODIUM" @default.
- NCIT_C66599 hasExactSynonym "Thiopental Sodium" @default.
- NCIT_C66599 inSubset NCIT_C63923 @default.
- NCIT_C66599 type Class @default.
- NCIT_C66599 isDefinedBy ncit.owl @default.
- NCIT_C66599 label "Thiopental Sodium" @default.
- NCIT_C66599 subClassOf NCIT_C1908 @default.
- NCIT_C66599 subClassOf NCIT_C1909 @default.
- NCIT_C66599 subClassOf NCIT_C245 @default.
- NCIT_C66599 subClassOf NCIT_C29756 @default.
- NCIT_C66599 subClassOf NCIT_C66599 @default.
- NCIT_C66599 subClassOf NCIT_C67084 @default.
- NCIT_C66599 subClassOf NCIT_C78272 @default.