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- NCIT_C66978 IAO_0000115 "A radioimmunoconjugate consisting of the chimeric monoclonal antibody cG250 linked to the low energy beta-emitting radioisotope Lutetium 177, via the bifunctional macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA), with potential antineoplastic activity. The antibody moiety of lutetium Lu-177-DOTA-chimeric monoclonal antibody cG250 binds to renal cell carcinoma (RCC) cells expressing the RCC-associated antigen G250; a cytotoxic dose of beta radiation is selectively delivered to G250-expressing RCC cells upon internalization of the radioimmunoconjugate." @default.
- NCIT_C66978 NCIT_A32 NCIT_C1909 @default.
- NCIT_C66978 NCIT_NHC0 "C66978" @default.
- NCIT_C66978 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C66978 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66978 NCIT_P108 "Lutetium Lu-177 Girentuximab" @default.
- NCIT_C66978 NCIT_P207 "C1881485" @default.
- NCIT_C66978 NCIT_P322 "GDC" @default.
- NCIT_C66978 NCIT_P329 "531051" @default.
- NCIT_C66978 NCIT_P330 "531051" @default.
- NCIT_C66978 NCIT_P366 "Lutetium_Lu_177-DOTA-Chimeric_Monoclonal_Antibody_cG250" @default.
- NCIT_C66978 NCIT_P375 "Lutetium Lu-177 Girentuximab" @default.
- NCIT_C66978 NCIT_P399 "531051" @default.
- NCIT_C66978 normalizedInformationContent "100" @default.
- NCIT_C66978 referenceCount "1" @default.
- NCIT_C66978 hasExactSynonym "177Lu-DOTA-cG250" @default.
- NCIT_C66978 hasExactSynonym "Lutetium Lu-177 Girentuximab" @default.
- NCIT_C66978 hasExactSynonym "Lutetium Lu-177-DOTA-Chimeric Monoclonal Antibody cG250" @default.
- NCIT_C66978 hasExactSynonym "Lutetium-177 Labeled cG250" @default.
- NCIT_C66978 inSubset NCIT_C128784 @default.
- NCIT_C66978 inSubset NCIT_C157711 @default.
- NCIT_C66978 inSubset NCIT_C157712 @default.
- NCIT_C66978 inSubset NCIT_C176424 @default.
- NCIT_C66978 inSubset NCIT_C177537 @default.
- NCIT_C66978 type Class @default.
- NCIT_C66978 isDefinedBy ncit.owl @default.
- NCIT_C66978 label "Lutetium Lu-177 Girentuximab" @default.
- NCIT_C66978 subClassOf NCIT_C129819 @default.
- NCIT_C66978 subClassOf NCIT_C1446 @default.
- NCIT_C66978 subClassOf NCIT_C1511 @default.
- NCIT_C66978 subClassOf NCIT_C1512 @default.
- NCIT_C66978 subClassOf NCIT_C1908 @default.
- NCIT_C66978 subClassOf NCIT_C1909 @default.
- NCIT_C66978 subClassOf NCIT_C2124 @default.
- NCIT_C66978 subClassOf NCIT_C274 @default.
- NCIT_C66978 subClassOf NCIT_C307 @default.
- NCIT_C66978 subClassOf NCIT_C308 @default.
- NCIT_C66978 subClassOf NCIT_C66978 @default.