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- NCIT_C67049 IAO_0000115 "A topical ointment containing a green tea polyphenol mixture (kunecatechins) with potential antiviral, antibacterial, antioxidant, and chemopreventive activities. Kunecatechins is a partially purified fraction of the aqueous extract of green tea leaves from Camellia sinensis and contains catechins and other green tea components. Catechins, polyphenolic antioxidant plant metabolites or flavonoids, comprise most of the drug substance in kunecatechins with epigallocatechin gallate (EGCG) present as the primary catechin. Catechins may inhibit basic functions of human papillomavirus (HPV), counteract specific changes in tumor cells, affect cell signaling, and stimulate the immune system. Topical application of kunecatechins ointment has been reported to reduce HPV-induced genital and anal warts through a not yet fully understood mechanism, which may involve anti-oxidative activity." @default.
- NCIT_C67049 NCIT_A32 NCIT_C1909 @default.
- NCIT_C67049 NCIT_NHC0 "C67049" @default.
- NCIT_C67049 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C67049 NCIT_P108 "Kunecatechins Ointment" @default.
- NCIT_C67049 NCIT_P207 "C1816306" @default.
- NCIT_C67049 NCIT_P302 "Genital and Perianal Warts" @default.
- NCIT_C67049 NCIT_P322 "GDC" @default.
- NCIT_C67049 NCIT_P329 "533915" @default.
- NCIT_C67049 NCIT_P330 "533915" @default.
- NCIT_C67049 NCIT_P366 "Kunecatechin_Ointment" @default.
- NCIT_C67049 NCIT_P375 "Kunecatechins Ointment" @default.
- NCIT_C67049 NCIT_P399 "533915" @default.
- NCIT_C67049 normalizedInformationContent "100" @default.
- NCIT_C67049 referenceCount "1" @default.
- NCIT_C67049 hasExactSynonym "Defined Green Tea Catechin Extract OIntment" @default.
- NCIT_C67049 hasExactSynonym "Kunecatechins Ointment" @default.
- NCIT_C67049 hasExactSynonym "Polyphenon E Ointment" @default.
- NCIT_C67049 hasExactSynonym "Polyphenon E Topical Ointment" @default.
- NCIT_C67049 hasExactSynonym "Veregen" @default.
- NCIT_C67049 inSubset NCIT_C128784 @default.
- NCIT_C67049 inSubset NCIT_C157711 @default.
- NCIT_C67049 inSubset NCIT_C157712 @default.
- NCIT_C67049 inSubset NCIT_C176424 @default.
- NCIT_C67049 inSubset NCIT_C177537 @default.
- NCIT_C67049 type Class @default.
- NCIT_C67049 isDefinedBy ncit.owl @default.
- NCIT_C67049 label "Kunecatechins Ointment" @default.
- NCIT_C67049 subClassOf NCIT_C1892 @default.
- NCIT_C67049 subClassOf NCIT_C1908 @default.
- NCIT_C67049 subClassOf NCIT_C1909 @default.
- NCIT_C67049 subClassOf NCIT_C67049 @default.