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- NCIT_C67079 IAO_0000115 "A fully human IgG2 monoclonal antibody directed against the human hepatocyte growth factor (HGF) with potential antineoplastic activity. Anti-HGF monoclonal antibody AMG 102 binds to and neutralizes HGF, preventing the binding of HGF to its receptor c-Met and so c-Met activation; inhibition of c-Met-mediated signal transduction may result in the induction of apoptosis in cells expressing c-Met. c-Met (HGF receptor or HGFR), a receptor tyrosine kinase overexpressed or mutated in a variety of epithelial cancer cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis." @default.
- NCIT_C67079 NCIT_A32 NCIT_C1909 @default.
- NCIT_C67079 NCIT_A7 NCIT_C20428 @default.
- NCIT_C67079 NCIT_NHC0 "C67079" @default.
- NCIT_C67079 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C67079 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C67079 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C67079 NCIT_P107 "Rilotumumab" @default.
- NCIT_C67079 NCIT_P108 "Rilotumumab" @default.
- NCIT_C67079 NCIT_P207 "C2743963" @default.
- NCIT_C67079 NCIT_P210 "872514-65-3" @default.
- NCIT_C67079 NCIT_P319 "51WEW898IJ" @default.
- NCIT_C67079 NCIT_P322 "CTRP" @default.
- NCIT_C67079 NCIT_P322 "FDA" @default.
- NCIT_C67079 NCIT_P322 "GDC" @default.
- NCIT_C67079 NCIT_P325 "A substance being studied in the treatment of cancer. It binds to a protein called hepatocyte growth factor (HGF), which may cause cancer cells to grow. Blocking this may cause cancer cells to die. AMG 102 is a type of monoclonal antibody." @default.
- NCIT_C67079 NCIT_P329 "536240" @default.
- NCIT_C67079 NCIT_P330 "536240" @default.
- NCIT_C67079 NCIT_P366 "Anti-HGF_Monoclonal_Antibody_AMG_102" @default.
- NCIT_C67079 NCIT_P375 "Rilotumumab" @default.
- NCIT_C67079 NCIT_P399 "536240" @default.
- NCIT_C67079 NCIT_R124 NCIT_C17710 @default.
- NCIT_C67079 NCIT_R124 NCIT_C17828 @default.
- NCIT_C67079 NCIT_R124 NCIT_C18219 @default.
- NCIT_C67079 NCIT_R124 NCIT_C19986 @default.
- NCIT_C67079 NCIT_R124 NCIT_C40474 @default.
- NCIT_C67079 normalizedInformationContent "100" @default.
- NCIT_C67079 referenceCount "1" @default.
- NCIT_C67079 hasExactSynonym "AMG 102" @default.
- NCIT_C67079 hasExactSynonym "Anti-HGF Monoclonal Antibody AMG 102" @default.
- NCIT_C67079 hasExactSynonym "Fully Human Anti-HGF Monoclonal Antibody AMG 102" @default.
- NCIT_C67079 hasExactSynonym "RILOTUMUMAB" @default.
- NCIT_C67079 hasExactSynonym "Rilotumumab" @default.
- NCIT_C67079 hasExactSynonym "anti-HGF monoclonal antibody AMG 102" @default.
- NCIT_C67079 inSubset NCIT_C116977 @default.
- NCIT_C67079 inSubset NCIT_C116978 @default.
- NCIT_C67079 inSubset NCIT_C128784 @default.
- NCIT_C67079 inSubset NCIT_C157711 @default.
- NCIT_C67079 inSubset NCIT_C157712 @default.
- NCIT_C67079 inSubset NCIT_C176424 @default.
- NCIT_C67079 inSubset NCIT_C177537 @default.
- NCIT_C67079 inSubset NCIT_C63923 @default.
- NCIT_C67079 type Class @default.
- NCIT_C67079 isDefinedBy ncit.owl @default.
- NCIT_C67079 label "Rilotumumab" @default.
- NCIT_C67079 subClassOf NCIT_C129821 @default.
- NCIT_C67079 subClassOf NCIT_C129822 @default.
- NCIT_C67079 subClassOf NCIT_C1908 @default.
- NCIT_C67079 subClassOf NCIT_C1909 @default.
- NCIT_C67079 subClassOf NCIT_C20401 @default.
- NCIT_C67079 subClassOf NCIT_C274 @default.
- NCIT_C67079 subClassOf NCIT_C307 @default.
- NCIT_C67079 subClassOf NCIT_C308 @default.
- NCIT_C67079 subClassOf NCIT_C67079 @default.