Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C679> ?p ?o ?g. }
Showing items 1 to 40 of
40
with 100 items per page.
- NCIT_C679 IAO_0000115 "The hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta-naltrexol reverse the effects of opioids by binding to various opioid receptors in the central nervous system CNS), including the mu-, kappa- and gamma-opioid receptors; opioid effects of analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence are inhibited. Naltrexone is longer-acting and more potent compared to naloxone." @default.
- NCIT_C679 NCIT_A6 NCIT_C62055 @default.
- NCIT_C679 NCIT_NHC0 "C679" @default.
- NCIT_C679 NCIT_P106 "Organic Chemical" @default.
- NCIT_C679 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C679 NCIT_P107 "Naltrexone Hydrochloride" @default.
- NCIT_C679 NCIT_P108 "Naltrexone Hydrochloride" @default.
- NCIT_C679 NCIT_P207 "C0355800" @default.
- NCIT_C679 NCIT_P210 "16676-29-2" @default.
- NCIT_C679 NCIT_P319 "Z6375YW9SF" @default.
- NCIT_C679 NCIT_P322 "CTRP" @default.
- NCIT_C679 NCIT_P322 "FDA" @default.
- NCIT_C679 NCIT_P325 "A drug that blocks the action of opiates (drugs used to treat pain). It may be used in the treatment of intravenous opiate addiction or alcohol dependence. Naltrexone hydrochloride is also being studied in the treatment of breast cancer. It may block the effects of the hormone estrogen, which causes some breast cancer cells to grow, or block the blood flow to tumors. It is a type of opiate antagonist." @default.
- NCIT_C679 NCIT_P329 "40818" @default.
- NCIT_C679 NCIT_P330 "40818" @default.
- NCIT_C679 NCIT_P350 "C20H23NO4.HCl" @default.
- NCIT_C679 NCIT_P366 "Naltrexone" @default.
- NCIT_C679 NCIT_P399 "40818" @default.
- NCIT_C679 normalizedInformationContent "100" @default.
- NCIT_C679 referenceCount "1" @default.
- NCIT_C679 hasExactSynonym "(5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one Hydrochloride" @default.
- NCIT_C679 hasExactSynonym "Depade" @default.
- NCIT_C679 hasExactSynonym "NALTREXONE HYDROCHLORIDE" @default.
- NCIT_C679 hasExactSynonym "Naltrexone Hydrochloride" @default.
- NCIT_C679 hasExactSynonym "Naltrexone.HCl" @default.
- NCIT_C679 hasExactSynonym "ReVia" @default.
- NCIT_C679 hasExactSynonym "Revia" @default.
- NCIT_C679 hasExactSynonym "naltrexone hydrochloride" @default.
- NCIT_C679 inSubset NCIT_C116977 @default.
- NCIT_C679 inSubset NCIT_C116978 @default.
- NCIT_C679 inSubset NCIT_C176424 @default.
- NCIT_C679 inSubset NCIT_C63923 @default.
- NCIT_C679 type Class @default.
- NCIT_C679 isDefinedBy ncit.owl @default.
- NCIT_C679 label "Naltrexone Hydrochloride" @default.
- NCIT_C679 subClassOf NCIT_C1908 @default.
- NCIT_C679 subClassOf NCIT_C1909 @default.
- NCIT_C679 subClassOf NCIT_C679 @default.
- NCIT_C679 subClassOf NCIT_C681 @default.
- NCIT_C679 subClassOf NCIT_C78272 @default.