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- NCIT_C68434 IAO_0000115 "The free fatty acid (FFA) form of eicosapentaenoic acid (EPA), a polyunsaturated long-chain fatty acid found in fish oil with a 20-carbon backbone and 5 double bonds, with potential supplementing, anti-inflammatory, anti-thrombotic, immunomodulating, anti-angiogenic and chemopreventive activities. Upon administration of icosapent, the free form of EPA is incorporated in cell membrane phospholipids and replaces arachidonic acid. This inhibits arachidonic acid conversion into thromboxanes and prostaglandin E2 (PGE2). Upon oral administration of icosapent, the EPA-FFA prevents and suppresses colonic neoplasia and reduces polyp formation and growth through as of yet not fully elucidated mechanisms." @default.
- NCIT_C68434 NCIT_NHC0 "C68434" @default.
- NCIT_C68434 NCIT_P106 "Organic Chemical" @default.
- NCIT_C68434 NCIT_P108 "Icosapent" @default.
- NCIT_C68434 NCIT_P207 "C1370123" @default.
- NCIT_C68434 NCIT_P210 "10417-94-4" @default.
- NCIT_C68434 NCIT_P210 "25377-48-4" @default.
- NCIT_C68434 NCIT_P319 "AAN7QOV9EA" @default.
- NCIT_C68434 NCIT_P322 "CRCH" @default.
- NCIT_C68434 NCIT_P322 "FDA" @default.
- NCIT_C68434 NCIT_P325 "Polyunsaturated fatty acid with 20 carbons and 5 double bonds at the 3rd, 6th, 9th, 12th and 15th carbons from the methyl end." @default.
- NCIT_C68434 NCIT_P329 "799811" @default.
- NCIT_C68434 NCIT_P330 "799811" @default.
- NCIT_C68434 NCIT_P350 "C20H30O2" @default.
- NCIT_C68434 NCIT_P353 "F20D5N3" @default.
- NCIT_C68434 NCIT_P354 "629" @default.
- NCIT_C68434 NCIT_P355 "g" @default.
- NCIT_C68434 NCIT_P366 "Timnodonic_Acid" @default.
- NCIT_C68434 NCIT_P368 "CHEBI:28364" @default.
- NCIT_C68434 NCIT_P399 "799811" @default.
- NCIT_C68434 normalizedInformationContent "100" @default.
- NCIT_C68434 referenceCount "1" @default.
- NCIT_C68434 hasExactSynonym "All-cis-icosa-5,8,11,14,17-pentaenoic acid" @default.
- NCIT_C68434 hasExactSynonym "EPA-FFA" @default.
- NCIT_C68434 hasExactSynonym "Eicosapentaenoic Acid n-3" @default.
- NCIT_C68434 hasExactSynonym "Eicosapentaenoic Acid-Free Fatty Acid" @default.
- NCIT_C68434 hasExactSynonym "Fatty Acid 20:5 n-3" @default.
- NCIT_C68434 hasExactSynonym "ICOSAPENT" @default.
- NCIT_C68434 hasExactSynonym "Icosapent" @default.
- NCIT_C68434 hasExactSynonym "Icosapentaenoic Acid n-3" @default.
- NCIT_C68434 hasExactSynonym "Timnodonic Acid" @default.
- NCIT_C68434 hasExactSynonym "cis-5,8,11,14,17-Eicosapentaenoic Acid" @default.
- NCIT_C68434 inSubset NCIT_C173381 @default.
- NCIT_C68434 inSubset NCIT_C173383 @default.
- NCIT_C68434 inSubset NCIT_C176424 @default.
- NCIT_C68434 inSubset NCIT_C63923 @default.
- NCIT_C68434 type Class @default.
- NCIT_C68434 isDefinedBy ncit.owl @default.
- NCIT_C68434 label "Icosapent" @default.
- NCIT_C68434 subClassOf NCIT_C1908 @default.
- NCIT_C68434 subClassOf NCIT_C1913 @default.
- NCIT_C68434 subClassOf NCIT_C1930 @default.
- NCIT_C68434 subClassOf NCIT_C1949 @default.
- NCIT_C68434 subClassOf NCIT_C2317 @default.
- NCIT_C68434 subClassOf NCIT_C493 @default.
- NCIT_C68434 subClassOf NCIT_C54060 @default.
- NCIT_C68434 subClassOf NCIT_C616 @default.
- NCIT_C68434 subClassOf NCIT_C67038 @default.
- NCIT_C68434 subClassOf NCIT_C67080 @default.
- NCIT_C68434 subClassOf NCIT_C68339 @default.
- NCIT_C68434 subClassOf NCIT_C68434 @default.
- NCIT_C68434 subClassOf NCIT_C68439 @default.
- NCIT_C68434 subClassOf NCIT_C718 @default.