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- NCIT_C689 IAO_0000115 "A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C." @default.
- NCIT_C689 NCIT_NHC0 "C689" @default.
- NCIT_C689 NCIT_P106 "Organic Chemical" @default.
- NCIT_C689 NCIT_P106 "Vitamin" @default.
- NCIT_C689 NCIT_P107 "Niacin" @default.
- NCIT_C689 NCIT_P108 "Niacin" @default.
- NCIT_C689 NCIT_P175 "169454" @default.
- NCIT_C689 NCIT_P207 "C0027996" @default.
- NCIT_C689 NCIT_P210 "59-67-6" @default.
- NCIT_C689 NCIT_P319 "2679MF687A" @default.
- NCIT_C689 NCIT_P322 "CRCH" @default.
- NCIT_C689 NCIT_P322 "CTRP" @default.
- NCIT_C689 NCIT_P322 "FDA" @default.
- NCIT_C689 NCIT_P325 "A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacin helps some enzymes work properly and helps skin, nerves, and the digestive tract stay healthy. Niacin is found in many plant and animal products. It is water-soluble (can dissolve in water) and must be taken in every day. Not enough niacin can cause a disease called pellagra (a condition marked by skin, nerve, and digestive disorders). A form of niacin is being studied in the prevention of skin and other types of cancer. Niacin may help to lower blood cholesterol." @default.
- NCIT_C689 NCIT_P325 "Water-soluble vitamin that is a cosubstrate or coenzyme with numerous dehydrogenases for the transfer of the hydride ion. (DRI)" @default.
- NCIT_C689 NCIT_P329 "38351" @default.
- NCIT_C689 NCIT_P330 "38351" @default.
- NCIT_C689 NCIT_P350 "C6H5NO2" @default.
- NCIT_C689 NCIT_P351 "Y" @default.
- NCIT_C689 NCIT_P352 "Y" @default.
- NCIT_C689 NCIT_P353 "NIA" @default.
- NCIT_C689 NCIT_P354 "406" @default.
- NCIT_C689 NCIT_P355 "mg" @default.
- NCIT_C689 NCIT_P358 "Y" @default.
- NCIT_C689 NCIT_P359 "Y" @default.
- NCIT_C689 NCIT_P366 "Niacin" @default.
- NCIT_C689 NCIT_P368 "CHEBI:15940" @default.
- NCIT_C689 NCIT_P399 "38351" @default.
- NCIT_C689 normalizedInformationContent "100" @default.
- NCIT_C689 referenceCount "1" @default.
- NCIT_C689 hasExactSynonym "3-Pyridinecarboxylic Acid" @default.
- NCIT_C689 hasExactSynonym "NIACIN" @default.
- NCIT_C689 hasExactSynonym "Niacin" @default.
- NCIT_C689 hasExactSynonym "Nicotinamide" @default.
- NCIT_C689 hasExactSynonym "Nicotinic Acid Amide" @default.
- NCIT_C689 hasExactSynonym "Nicotinic Acid" @default.
- NCIT_C689 hasExactSynonym "Nicotinic acid" @default.
- NCIT_C689 hasExactSynonym "Vitamin B-3" @default.
- NCIT_C689 hasExactSynonym "Vitamin B3" @default.
- NCIT_C689 hasExactSynonym "niacin" @default.
- NCIT_C689 hasExactSynonym "nicotinic acid" @default.
- NCIT_C689 hasExactSynonym "vitamin B3" @default.
- NCIT_C689 inSubset NCIT_C116977 @default.
- NCIT_C689 inSubset NCIT_C116978 @default.
- NCIT_C689 inSubset NCIT_C142799 @default.
- NCIT_C689 inSubset NCIT_C176424 @default.
- NCIT_C689 inSubset NCIT_C63923 @default.
- NCIT_C689 type Class @default.
- NCIT_C689 isDefinedBy ncit.owl @default.
- NCIT_C689 label "Niacin" @default.
- NCIT_C689 subClassOf NCIT_C1551 @default.
- NCIT_C689 subClassOf NCIT_C1908 @default.
- NCIT_C689 subClassOf NCIT_C1930 @default.
- NCIT_C689 subClassOf NCIT_C1949 @default.
- NCIT_C689 subClassOf NCIT_C45812 @default.
- NCIT_C689 subClassOf NCIT_C54060 @default.
- NCIT_C689 subClassOf NCIT_C689 @default.
- NCIT_C689 subClassOf NCIT_C944 @default.