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- NCIT_C68931 IAO_0000115 "A water-soluble prodrug of a cyanoguanidine compound with potential antineoplastic activity. In vivo, teglarinad chloride is rapidly converted into active drug through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, the active drug appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis." @default.
- NCIT_C68931 NCIT_A32 NCIT_C1909 @default.
- NCIT_C68931 NCIT_A6 NCIT_C90746 @default.
- NCIT_C68931 NCIT_NHC0 "C68931" @default.
- NCIT_C68931 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C68931 NCIT_P107 "Teglarinad Chloride" @default.
- NCIT_C68931 NCIT_P108 "Teglarinad Chloride" @default.
- NCIT_C68931 NCIT_P207 "C2346839" @default.
- NCIT_C68931 NCIT_P210 "432037-57-5" @default.
- NCIT_C68931 NCIT_P319 "D6V5QYX9MZ" @default.
- NCIT_C68931 NCIT_P322 "CTRP" @default.
- NCIT_C68931 NCIT_P322 "FDA" @default.
- NCIT_C68931 NCIT_P322 "GDC" @default.
- NCIT_C68931 NCIT_P329 "547816" @default.
- NCIT_C68931 NCIT_P330 "547816" @default.
- NCIT_C68931 NCIT_P350 "C30H43ClN5O8.Cl" @default.
- NCIT_C68931 NCIT_P366 "Apoptosis_Inducer_GMX1777" @default.
- NCIT_C68931 NCIT_P375 "Teglarinad Chloride" @default.
- NCIT_C68931 NCIT_P399 "547816" @default.
- NCIT_C68931 NCIT_R125 NCIT_C17828 @default.
- NCIT_C68931 NCIT_R125 NCIT_C20150 @default.
- NCIT_C68931 NCIT_R125 NCIT_C20480 @default.
- NCIT_C68931 NCIT_R125 NCIT_C40715 @default.
- NCIT_C68931 NCIT_R125 NCIT_C41515 @default.
- NCIT_C68931 NCIT_R125 NCIT_C51037 @default.
- NCIT_C68931 normalizedInformationContent "100" @default.
- NCIT_C68931 referenceCount "1" @default.
- NCIT_C68931 hasExactSynonym "CHS828 Prodrug" @default.
- NCIT_C68931 hasExactSynonym "EB1627" @default.
- NCIT_C68931 hasExactSynonym "GMX1777" @default.
- NCIT_C68931 hasExactSynonym "Pyridinium, 4-[[[[6-(4-chlorophenoxy)hexyl]amino](cyanoamino) methylene]amino]-1-(3-oxo-2,4,7,10,13,16-hexaoxaheptadec-1-yl)-, chloride" @default.
- NCIT_C68931 hasExactSynonym "TEGLARINAD CHLORIDE" @default.
- NCIT_C68931 hasExactSynonym "Teglarinad Chloride" @default.
- NCIT_C68931 inSubset NCIT_C116977 @default.
- NCIT_C68931 inSubset NCIT_C116978 @default.
- NCIT_C68931 inSubset NCIT_C128784 @default.
- NCIT_C68931 inSubset NCIT_C157711 @default.
- NCIT_C68931 inSubset NCIT_C157712 @default.
- NCIT_C68931 inSubset NCIT_C176424 @default.
- NCIT_C68931 inSubset NCIT_C177537 @default.
- NCIT_C68931 inSubset NCIT_C63923 @default.
- NCIT_C68931 type Class @default.
- NCIT_C68931 isDefinedBy ncit.owl @default.
- NCIT_C68931 label "Teglarinad Chloride" @default.
- NCIT_C68931 subClassOf B2a55a198c9f86aa95fec823eb2898801 @default.
- NCIT_C68931 subClassOf Be4f75e4cde8300e398395edc9145f4e5 @default.
- NCIT_C68931 subClassOf NCIT_C129824 @default.
- NCIT_C68931 subClassOf NCIT_C129825 @default.
- NCIT_C68931 subClassOf NCIT_C1908 @default.
- NCIT_C68931 subClassOf NCIT_C1909 @default.
- NCIT_C68931 subClassOf NCIT_C2189 @default.
- NCIT_C68931 subClassOf NCIT_C274 @default.
- NCIT_C68931 subClassOf NCIT_C471 @default.
- NCIT_C68931 subClassOf NCIT_C68931 @default.