Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C68936> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- NCIT_C68936 IAO_0000115 "An orally available small molecule with potential antineoplastic activity. Quizartinib selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis. Mutations in FLT3, resulting in constitutive activation, are the most frequent genetic alterations in acute myeloid leukemia (AML) and occur in approximately one-third of AML cases." @default.
- NCIT_C68936 NCIT_A24 NCIT_C274 @default.
- NCIT_C68936 NCIT_A32 NCIT_C1909 @default.
- NCIT_C68936 NCIT_A5 NCIT_C97272 @default.
- NCIT_C68936 NCIT_A7 NCIT_C17322 @default.
- NCIT_C68936 NCIT_A7 NCIT_C17328 @default.
- NCIT_C68936 NCIT_A7 NCIT_C17392 @default.
- NCIT_C68936 NCIT_A7 NCIT_C26202 @default.
- NCIT_C68936 NCIT_NHC0 "C68936" @default.
- NCIT_C68936 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C68936 NCIT_P107 "Quizartinib" @default.
- NCIT_C68936 NCIT_P108 "Quizartinib" @default.
- NCIT_C68936 NCIT_P207 "C2980091" @default.
- NCIT_C68936 NCIT_P210 "950769-58-1" @default.
- NCIT_C68936 NCIT_P319 "7LA4O6Q0D3" @default.
- NCIT_C68936 NCIT_P322 "CTRP" @default.
- NCIT_C68936 NCIT_P322 "FDA" @default.
- NCIT_C68936 NCIT_P322 "GDC" @default.
- NCIT_C68936 NCIT_P322 "PCDC" @default.
- NCIT_C68936 NCIT_P350 "C29H32N6O4S" @default.
- NCIT_C68936 NCIT_P366 "FLT-3_Kinase_Inhibitor_AC220" @default.
- NCIT_C68936 NCIT_P375 "Quizartinib" @default.
- NCIT_C68936 normalizedInformationContent "100" @default.
- NCIT_C68936 referenceCount "1" @default.
- NCIT_C68936 hasExactSynonym "(2E)-N-(4-(3-Chloro-4-Fluoroanilino)-7-(((3S)-Oxolan-3-Yl)Oxy)Quinoxazolin-6-yl)-4-(Dimethylamino)but-2-Enamide" @default.
- NCIT_C68936 hasExactSynonym "AC-220" @default.
- NCIT_C68936 hasExactSynonym "AC010220" @default.
- NCIT_C68936 hasExactSynonym "AC220" @default.
- NCIT_C68936 hasExactSynonym "ASP 2689" @default.
- NCIT_C68936 hasExactSynonym "ASP-2689" @default.
- NCIT_C68936 hasExactSynonym "ASP2689" @default.
- NCIT_C68936 hasExactSynonym "N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo [2,1-b] [1,3] benzothiazol 2-yl]phenyl}urea" @default.
- NCIT_C68936 hasExactSynonym "QUIZARTINIB" @default.
- NCIT_C68936 hasExactSynonym "Quizartinib" @default.
- NCIT_C68936 hasExactSynonym "Vanflyta" @default.
- NCIT_C68936 inSubset NCIT_C116977 @default.
- NCIT_C68936 inSubset NCIT_C116978 @default.
- NCIT_C68936 inSubset NCIT_C128784 @default.
- NCIT_C68936 inSubset NCIT_C157711 @default.
- NCIT_C68936 inSubset NCIT_C157712 @default.
- NCIT_C68936 inSubset NCIT_C173234 @default.
- NCIT_C68936 inSubset NCIT_C174019 @default.
- NCIT_C68936 inSubset NCIT_C177537 @default.
- NCIT_C68936 inSubset NCIT_C63923 @default.
- NCIT_C68936 type Class @default.
- NCIT_C68936 isDefinedBy ncit.owl @default.
- NCIT_C68936 label "Quizartinib" @default.
- NCIT_C68936 subClassOf NCIT_C124800 @default.
- NCIT_C68936 subClassOf NCIT_C129820 @default.
- NCIT_C68936 subClassOf NCIT_C129824 @default.
- NCIT_C68936 subClassOf NCIT_C129825 @default.
- NCIT_C68936 subClassOf NCIT_C1404 @default.
- NCIT_C68936 subClassOf NCIT_C159198 @default.
- NCIT_C68936 subClassOf NCIT_C159199 @default.
- NCIT_C68936 subClassOf NCIT_C163758 @default.
- NCIT_C68936 subClassOf NCIT_C163790 @default.
- NCIT_C68936 subClassOf NCIT_C163999 @default.
- NCIT_C68936 subClassOf NCIT_C164037 @default.
- NCIT_C68936 subClassOf NCIT_C1908 @default.
- NCIT_C68936 subClassOf NCIT_C1909 @default.
- NCIT_C68936 subClassOf NCIT_C1967 @default.
- NCIT_C68936 subClassOf NCIT_C198643 @default.
- NCIT_C68936 subClassOf NCIT_C198646 @default.
- NCIT_C68936 subClassOf NCIT_C2189 @default.
- NCIT_C68936 subClassOf NCIT_C274 @default.
- NCIT_C68936 subClassOf NCIT_C308 @default.
- NCIT_C68936 subClassOf NCIT_C471 @default.
- NCIT_C68936 subClassOf NCIT_C68936 @default.