Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C68963> ?p ?o ?g. }
Showing items 1 to 42 of
42
with 100 items per page.
- NCIT_C68963 IAO_0000115 "A selective, orally active small molecule, targeting protein kinase B (PKB or AKT) and ribosomal protein S6 Kinase (p70S6K), with potential antineoplastic activity. XL418 inhibits the activities of PKB and p70S6K, both acting downstream of phosphoinosotide-3 kinase (PI3K). These kinases are often upregulated in a variety of cancers. Inhibition of PKB by this agent will induce apoptosis, while inhibition of p70S6K will result in the inhibition of translation within tumor cells." @default.
- NCIT_C68963 NCIT_A32 NCIT_C1909 @default.
- NCIT_C68963 NCIT_A7 NCIT_C41625 @default.
- NCIT_C68963 NCIT_NHC0 "C68963" @default.
- NCIT_C68963 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C68963 NCIT_P108 "Serine/Threonine Kinase Inhibitor XL418" @default.
- NCIT_C68963 NCIT_P208 "CL374493" @default.
- NCIT_C68963 NCIT_P210 "871343-09-8" @default.
- NCIT_C68963 NCIT_P319 "OLJ18SRI8A" @default.
- NCIT_C68963 NCIT_P322 "FDA" @default.
- NCIT_C68963 NCIT_P322 "GDC" @default.
- NCIT_C68963 NCIT_P329 "546978" @default.
- NCIT_C68963 NCIT_P330 "546978" @default.
- NCIT_C68963 NCIT_P366 "Serine_Threonine_Kinase_Inhibitor_XL418" @default.
- NCIT_C68963 NCIT_P375 "Serine/Threonine Kinase Inhibitor XL418" @default.
- NCIT_C68963 NCIT_P399 "546978" @default.
- NCIT_C68963 normalizedInformationContent "100" @default.
- NCIT_C68963 referenceCount "1" @default.
- NCIT_C68963 hasExactSynonym "Serine/Threonine Kinase Inhibitor XL418" @default.
- NCIT_C68963 hasExactSynonym "XL-418" @default.
- NCIT_C68963 hasExactSynonym "XL418" @default.
- NCIT_C68963 inSubset NCIT_C128784 @default.
- NCIT_C68963 inSubset NCIT_C157711 @default.
- NCIT_C68963 inSubset NCIT_C157712 @default.
- NCIT_C68963 inSubset NCIT_C176424 @default.
- NCIT_C68963 inSubset NCIT_C177537 @default.
- NCIT_C68963 inSubset NCIT_C63923 @default.
- NCIT_C68963 type Class @default.
- NCIT_C68963 isDefinedBy ncit.owl @default.
- NCIT_C68963 label "Serine/Threonine Kinase Inhibitor XL418" @default.
- NCIT_C68963 subClassOf NCIT_C129824 @default.
- NCIT_C68963 subClassOf NCIT_C129825 @default.
- NCIT_C68963 subClassOf NCIT_C1404 @default.
- NCIT_C68963 subClassOf NCIT_C155764 @default.
- NCIT_C68963 subClassOf NCIT_C1742 @default.
- NCIT_C68963 subClassOf NCIT_C1908 @default.
- NCIT_C68963 subClassOf NCIT_C1909 @default.
- NCIT_C68963 subClassOf NCIT_C2189 @default.
- NCIT_C68963 subClassOf NCIT_C274 @default.
- NCIT_C68963 subClassOf NCIT_C471 @default.
- NCIT_C68963 subClassOf NCIT_C61074 @default.
- NCIT_C68963 subClassOf NCIT_C68963 @default.