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- NCIT_C702 IAO_0000115 "The orally bioavailable acetate salt of norethindrone, a synthetic progestin with some anabolic, estrogenic, and androgenic activities. As do all progestins, norethindrone binds to and activates nuclear progesterone receptors (PRs) in target tissues such as the pituitary and reproductive system; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes, followed by various transcriptional events and histone acetylation. Physiological effects include the inhibition of luteinizing hormone (LH) release, an increase in the endometrial luteal-phase, and alterations in endocervical mucus secretion." @default.
- NCIT_C702 NCIT_A6 NCIT_C62059 @default.
- NCIT_C702 NCIT_NHC0 "C702" @default.
- NCIT_C702 NCIT_P106 "Organic Chemical" @default.
- NCIT_C702 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C702 NCIT_P108 "Norethindrone Acetate" @default.
- NCIT_C702 NCIT_P175 "9564" @default.
- NCIT_C702 NCIT_P207 "C0699165" @default.
- NCIT_C702 NCIT_P210 "51-98-9" @default.
- NCIT_C702 NCIT_P319 "9S44LIC7OJ" @default.
- NCIT_C702 NCIT_P322 "FDA" @default.
- NCIT_C702 NCIT_P329 "39254" @default.
- NCIT_C702 NCIT_P330 "39254" @default.
- NCIT_C702 NCIT_P350 "C22H28O3" @default.
- NCIT_C702 NCIT_P366 "Norethindrone" @default.
- NCIT_C702 NCIT_P399 "39254" @default.
- NCIT_C702 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C702 referenceCount "2" @default.
- NCIT_C702 hasExactSynonym "Aygestin" @default.
- NCIT_C702 hasExactSynonym "NORETHINDRONE ACETATE" @default.
- NCIT_C702 hasExactSynonym "Nor-Q.D." @default.
- NCIT_C702 hasExactSynonym "Norethindrone Acetate" @default.
- NCIT_C702 hasExactSynonym "Norethindrone acetate" @default.
- NCIT_C702 hasExactSynonym "Norethisterone Acetate" @default.
- NCIT_C702 hasExactSynonym "Norethisterone acetate" @default.
- NCIT_C702 hasExactSynonym "Norlutate" @default.
- NCIT_C702 hasExactSynonym "Ortho Micronor" @default.
- NCIT_C702 inSubset NCIT_C176424 @default.
- NCIT_C702 inSubset NCIT_C63923 @default.
- NCIT_C702 type Class @default.
- NCIT_C702 isDefinedBy ncit.owl @default.
- NCIT_C702 label "Norethindrone Acetate" @default.
- NCIT_C702 subClassOf NCIT_C147908 @default.
- NCIT_C702 subClassOf NCIT_C1636 @default.
- NCIT_C702 subClassOf NCIT_C1908 @default.
- NCIT_C702 subClassOf NCIT_C1909 @default.
- NCIT_C702 subClassOf NCIT_C548 @default.
- NCIT_C702 subClassOf NCIT_C702 @default.
- NCIT_C702 subClassOf NCIT_C776 @default.