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- NCIT_C704 IAO_0000115 "The hydrochloride salt form of nortriptyline, a tricyclic antidepressant agent used for short-term treatment of various forms of depression. Nortriptyline blocks the norepinephrine presynaptic receptors, thereby blocking the reuptake of this neurotransmitter and raising the concentration in the synaptic cleft in the CNS. Nortriptyline also binds to alpha-adrenergic, histaminergic and cholinergic receptors. Long-term treatment with nortriptyline produces a downregulation of adrenergic receptors due to the increased stimulation of these receptors." @default.
- NCIT_C704 NCIT_A6 NCIT_C62060 @default.
- NCIT_C704 NCIT_NHC0 "C704" @default.
- NCIT_C704 NCIT_P106 "Organic Chemical" @default.
- NCIT_C704 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C704 NCIT_P108 "Nortriptyline Hydrochloride" @default.
- NCIT_C704 NCIT_P175 "169453" @default.
- NCIT_C704 NCIT_P207 "C0700459" @default.
- NCIT_C704 NCIT_P210 "894-71-3" @default.
- NCIT_C704 NCIT_P302 "Depression" @default.
- NCIT_C704 NCIT_P319 "00FN6IH15D" @default.
- NCIT_C704 NCIT_P322 "FDA" @default.
- NCIT_C704 NCIT_P329 "41535" @default.
- NCIT_C704 NCIT_P330 "41535" @default.
- NCIT_C704 NCIT_P350 "C19H21N.HCl" @default.
- NCIT_C704 NCIT_P366 "Nortriptyline" @default.
- NCIT_C704 NCIT_P399 "41535" @default.
- NCIT_C704 NCIT_R122 NCIT_C16484 @default.
- NCIT_C704 NCIT_R122 NCIT_C16486 @default.
- NCIT_C704 NCIT_R122 NCIT_C16554 @default.
- NCIT_C704 NCIT_R122 NCIT_C16865 @default.
- NCIT_C704 NCIT_R122 NCIT_C16946 @default.
- NCIT_C704 NCIT_R122 NCIT_C17021 @default.
- NCIT_C704 NCIT_R122 NCIT_C17287 @default.
- NCIT_C704 NCIT_R122 NCIT_C20027 @default.
- NCIT_C704 NCIT_R122 NCIT_C26548 @default.
- NCIT_C704 NCIT_R122 NCIT_C28459 @default.
- NCIT_C704 normalizedInformationContent "100" @default.
- NCIT_C704 referenceCount "1" @default.
- NCIT_C704 hasExactSynonym "1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, Hydrochloride" @default.
- NCIT_C704 hasExactSynonym "Allegron" @default.
- NCIT_C704 hasExactSynonym "NORTRIPTYLINE HYDROCHLORIDE" @default.
- NCIT_C704 hasExactSynonym "Norpress" @default.
- NCIT_C704 hasExactSynonym "Nortriptyline Hydrochloride" @default.
- NCIT_C704 hasExactSynonym "Pamelor" @default.
- NCIT_C704 inSubset NCIT_C176424 @default.
- NCIT_C704 inSubset NCIT_C63923 @default.
- NCIT_C704 type Class @default.
- NCIT_C704 isDefinedBy ncit.owl @default.
- NCIT_C704 label "Nortriptyline Hydrochloride" @default.
- NCIT_C704 subClassOf B863d588e8d21d1494bfccee823dc5dda @default.
- NCIT_C704 subClassOf Bd683dd5e7449110b383aa91aa6311dbf @default.
- NCIT_C704 subClassOf NCIT_C1908 @default.
- NCIT_C704 subClassOf NCIT_C1909 @default.
- NCIT_C704 subClassOf NCIT_C265 @default.
- NCIT_C704 subClassOf NCIT_C704 @default.
- NCIT_C704 subClassOf NCIT_C78272 @default.
- NCIT_C704 subClassOf NCIT_C94727 @default.