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- NCIT_C70675 IAO_0000115 "A gadolinium-based, hydrophilic, macrocyclic, electrically neutral contrast agent used in contrast-enhanced MRI (CE-MRI). Gadobutrol is a non-ionic, paramagnetic complex consisting of gadolinium (Gd3+) chelated with the macrocyclic compound dihydroxy-hydroxymethylpropyl-tetraazacyclododecane-triacetic acid (butrol). Following intravenous administration, gadobutrol may increase MRI sensitivity for the detection of tumors and inflammatory and demyelinating diseases of the central nervous system (CNS) that are associated with areas with blood-brain barrier defects due to altered perfusion or an enlarged extracellular space. This agent is eliminated in an unchanged form via the kidneys; extra-renal elimination is negligible." @default.
- NCIT_C70675 NCIT_NHC0 "C70675" @default.
- NCIT_C70675 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C70675 NCIT_P106 "Organic Chemical" @default.
- NCIT_C70675 NCIT_P107 "Gadobutrol" @default.
- NCIT_C70675 NCIT_P108 "Gadobutrol" @default.
- NCIT_C70675 NCIT_P207 "C0291216" @default.
- NCIT_C70675 NCIT_P210 "138071-82-6" @default.
- NCIT_C70675 NCIT_P302 "Diagnostic Magnetic Resonance Imaging" @default.
- NCIT_C70675 NCIT_P319 "1BJ477IO2L" @default.
- NCIT_C70675 NCIT_P322 "CTRP" @default.
- NCIT_C70675 NCIT_P322 "FDA" @default.
- NCIT_C70675 NCIT_P329 "570641" @default.
- NCIT_C70675 NCIT_P330 "570641" @default.
- NCIT_C70675 NCIT_P350 "C18H31N4O9.Gd" @default.
- NCIT_C70675 NCIT_P366 "Gadobutrol" @default.
- NCIT_C70675 NCIT_P399 "570641" @default.
- NCIT_C70675 normalizedInformationContent "100" @default.
- NCIT_C70675 referenceCount "1" @default.
- NCIT_C70675 hasExactSynonym "(10-((1RS,2SR)-2,3-Dihydroxy-1-(hydroxymethyl)propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-))gadolinium" @default.
- NCIT_C70675 hasExactSynonym "BAY86-4875" @default.
- NCIT_C70675 hasExactSynonym "GADOBUTROL" @default.
- NCIT_C70675 hasExactSynonym "Gadavist" @default.
- NCIT_C70675 hasExactSynonym "Gadobutrol" @default.
- NCIT_C70675 hasExactSynonym "Gadograf" @default.
- NCIT_C70675 hasExactSynonym "Gadovist" @default.
- NCIT_C70675 hasExactSynonym "Protovis" @default.
- NCIT_C70675 hasExactSynonym "ZK 135079" @default.
- NCIT_C70675 inSubset NCIT_C116977 @default.
- NCIT_C70675 inSubset NCIT_C116978 @default.
- NCIT_C70675 inSubset NCIT_C176424 @default.
- NCIT_C70675 inSubset NCIT_C63923 @default.
- NCIT_C70675 type Class @default.
- NCIT_C70675 isDefinedBy ncit.owl @default.
- NCIT_C70675 label "Gadobutrol" @default.
- NCIT_C70675 subClassOf NCIT_C1908 @default.
- NCIT_C70675 subClassOf NCIT_C1932 @default.
- NCIT_C70675 subClassOf NCIT_C1966 @default.
- NCIT_C70675 subClassOf NCIT_C360 @default.
- NCIT_C70675 subClassOf NCIT_C390 @default.
- NCIT_C70675 subClassOf NCIT_C45678 @default.
- NCIT_C70675 subClassOf NCIT_C62358 @default.
- NCIT_C70675 subClassOf NCIT_C70675 @default.
- NCIT_C70675 subClassOf NCIT_C802 @default.