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- NCIT_C70792 IAO_0000115 "A recombinant, fully human monoclonal antibody directed against human vascular endothelial growth factor receptor 2 (VEGFR-2) with antiangiogenesis activity. Ramucirumab specifically binds to and inhibits VEGFR-2, which may result in an inhibition of tumor angiogenesis and a decrease in tumor nutrient supply. VEGFR-2 is a pro-angiogenic growth factor receptor tyrosine kinase expressed by endothelial cells." @default.
- NCIT_C70792 NCIT_A32 NCIT_C1909 @default.
- NCIT_C70792 NCIT_A7 NCIT_C28496 @default.
- NCIT_C70792 NCIT_NHC0 "C70792" @default.
- NCIT_C70792 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C70792 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C70792 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C70792 NCIT_P107 "Ramucirumab" @default.
- NCIT_C70792 NCIT_P108 "Ramucirumab" @default.
- NCIT_C70792 NCIT_P207 "C2742502" @default.
- NCIT_C70792 NCIT_P210 "947687-13-0" @default.
- NCIT_C70792 NCIT_P302 "metastatic colorectal cancer (mCRC); advanced or metastatic, gastric or gastroesophageal junction (GEJ) adenocarcinoma; hepatocellular carcinoma (HCC) in patients who have an alpha fetoprotein (AFP) of ≥ 400 ng/mL" @default.
- NCIT_C70792 NCIT_P302 "multicentric Castleman's disease (MCD)" @default.
- NCIT_C70792 NCIT_P319 "D99YVK4L0X" @default.
- NCIT_C70792 NCIT_P322 "CTRP" @default.
- NCIT_C70792 NCIT_P322 "FDA" @default.
- NCIT_C70792 NCIT_P322 "GDC" @default.
- NCIT_C70792 NCIT_P325 "A substance being studied in the treatment of breast cancer that has come back. It binds to receptors for a protein called vascular endothelial growth factor (VEGF). This keeps VEGF from binding to the receptors and may stop the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent and a type of monoclonal antibody." @default.
- NCIT_C70792 NCIT_P329 "570535" @default.
- NCIT_C70792 NCIT_P330 "570535" @default.
- NCIT_C70792 NCIT_P366 "Anti-VEGFR-2_Fully_Human_Monoclonal_Antibody_IMC-1121B" @default.
- NCIT_C70792 NCIT_P375 "Ramucirumab" @default.
- NCIT_C70792 NCIT_P399 "570535" @default.
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- NCIT_C70792 normalizedInformationContent "87.123597049860606" @default.
- NCIT_C70792 referenceCount "7" @default.
- NCIT_C70792 hasExactSynonym "Anti-VEGFR-2 Fully Human Monoclonal Antibody IMC-1121B" @default.
- NCIT_C70792 hasExactSynonym "Cyramza" @default.
- NCIT_C70792 hasExactSynonym "IMC-1121B" @default.
- NCIT_C70792 hasExactSynonym "LY3009806" @default.
- NCIT_C70792 hasExactSynonym "Monoclonal Antibody HGS-ETR2" @default.
- NCIT_C70792 hasExactSynonym "RAMUCIRUMAB" @default.
- NCIT_C70792 hasExactSynonym "Ramucirumab" @default.
- NCIT_C70792 hasExactSynonym "anti-VEGFR-2 fully human monoclonal antibody IMC-1121B" @default.
- NCIT_C70792 hasExactSynonym "ramucirumab" @default.
- NCIT_C70792 inSubset NCIT_C116977 @default.
- NCIT_C70792 inSubset NCIT_C116978 @default.
- NCIT_C70792 inSubset NCIT_C128784 @default.
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- NCIT_C70792 inSubset NCIT_C63923 @default.
- NCIT_C70792 type Class @default.
- NCIT_C70792 isDefinedBy ncit.owl @default.
- NCIT_C70792 label "Ramucirumab" @default.
- NCIT_C70792 subClassOf B58256c276992e23b15948e0f9809c612 @default.
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