Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C71532> ?p ?o ?g. }
Showing items 1 to 35 of
35
with 100 items per page.
- NCIT_C71532 IAO_0000115 "An orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic activity. Lonaprisan is a pure, highly receptor-selective progesterone receptor (PR) antagonist; binding of this agent to PRs inhibits PR activation and the associated proliferative effects. Unlike many other antiprogestins such as mifepristone, this agent does not appear to convert to an agonist in the presence of protein kinase A (PKA) activators and shows high antiprogestagenic activity on both progesterone receptor (PR) isoforms PR-A and PR-B." @default.
- NCIT_C71532 NCIT_NHC0 "C71532" @default.
- NCIT_C71532 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C71532 NCIT_P108 "Lonaprisan" @default.
- NCIT_C71532 NCIT_P171 "11150172" @default.
- NCIT_C71532 NCIT_P207 "C2347691" @default.
- NCIT_C71532 NCIT_P210 "211254-73-8" @default.
- NCIT_C71532 NCIT_P302 "Treatment of progesterone receptor positive breast cancer" @default.
- NCIT_C71532 NCIT_P319 "F5Z5EL4D26" @default.
- NCIT_C71532 NCIT_P322 "FDA" @default.
- NCIT_C71532 NCIT_P329 "579241" @default.
- NCIT_C71532 NCIT_P330 "579241" @default.
- NCIT_C71532 NCIT_P350 "C28H29F5O3" @default.
- NCIT_C71532 NCIT_P366 "Progesterone-Receptor_Antagonist_ZK_230211" @default.
- NCIT_C71532 NCIT_P399 "579241" @default.
- NCIT_C71532 normalizedInformationContent "100" @default.
- NCIT_C71532 referenceCount "1" @default.
- NCIT_C71532 hasExactSynonym "11 beta-(4-acetylphenyl)-20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17 alpha-pregna-5,9-dien-3-one" @default.
- NCIT_C71532 hasExactSynonym "BAY86-5044" @default.
- NCIT_C71532 hasExactSynonym "LONAPRISAN" @default.
- NCIT_C71532 hasExactSynonym "Lonaprisan" @default.
- NCIT_C71532 hasExactSynonym "Progesterone Receptor Antagonist ZK 230211" @default.
- NCIT_C71532 hasExactSynonym "ZK 230211" @default.
- NCIT_C71532 hasExactSynonym "ZK-PRA" @default.
- NCIT_C71532 inSubset NCIT_C176424 @default.
- NCIT_C71532 inSubset NCIT_C63923 @default.
- NCIT_C71532 type Class @default.
- NCIT_C71532 isDefinedBy ncit.owl @default.
- NCIT_C71532 label "Lonaprisan" @default.
- NCIT_C71532 subClassOf NCIT_C147908 @default.
- NCIT_C71532 subClassOf NCIT_C1891 @default.
- NCIT_C71532 subClassOf NCIT_C1908 @default.
- NCIT_C71532 subClassOf NCIT_C1909 @default.
- NCIT_C71532 subClassOf NCIT_C547 @default.
- NCIT_C71532 subClassOf NCIT_C71532 @default.