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- NCIT_C71534 IAO_0000115 "An inhalation aerosol formulation containing budesonide and the fumarate dihydrate salt of formoterol with anti-inflammatory and bronchial smooth muscle-relaxing activities. The synthetic corticosteroid steroid budesonide binds to intracellular glucocorticosteroid receptors (GRs), exhibiting inhibitory activities against multiple cell types and mediators associated with allergic inflammation. The long-acting beta-adrenergic receptor agonist formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP); increased intracellular cAMP result in the relaxation of bronchial smooth muscle and inhibition of the cellular release of mediators of immediate hypersensitivity, especially from mast cells." @default.
- NCIT_C71534 NCIT_NHC0 "C71534" @default.
- NCIT_C71534 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C71534 NCIT_P108 "Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol" @default.
- NCIT_C71534 NCIT_P207 "C1121854" @default.
- NCIT_C71534 NCIT_P329 "579574" @default.
- NCIT_C71534 NCIT_P330 "579574" @default.
- NCIT_C71534 NCIT_P366 "Budesonide_Formoterol_Fumarate_Dihydrate" @default.
- NCIT_C71534 NCIT_P399 "579574" @default.
- NCIT_C71534 NCIT_R122 NCIT_C16484 @default.
- NCIT_C71534 NCIT_R122 NCIT_C16486 @default.
- NCIT_C71534 NCIT_R122 NCIT_C16554 @default.
- NCIT_C71534 NCIT_R122 NCIT_C16865 @default.
- NCIT_C71534 NCIT_R122 NCIT_C16946 @default.
- NCIT_C71534 NCIT_R122 NCIT_C17021 @default.
- NCIT_C71534 NCIT_R122 NCIT_C17573 @default.
- NCIT_C71534 NCIT_R122 NCIT_C20027 @default.
- NCIT_C71534 NCIT_R122 NCIT_C26548 @default.
- NCIT_C71534 NCIT_R122 NCIT_C28459 @default.
- NCIT_C71534 normalizedInformationContent "100" @default.
- NCIT_C71534 referenceCount "1" @default.
- NCIT_C71534 hasExactSynonym "Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol" @default.
- NCIT_C71534 hasExactSynonym "Symbicort Turbuhaler" @default.
- NCIT_C71534 inSubset NCIT_C173381 @default.
- NCIT_C71534 inSubset NCIT_C173383 @default.
- NCIT_C71534 inSubset NCIT_C176424 @default.
- NCIT_C71534 type Class @default.
- NCIT_C71534 isDefinedBy ncit.owl @default.
- NCIT_C71534 label "Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol" @default.
- NCIT_C71534 subClassOf NCIT_C147908 @default.
- NCIT_C71534 subClassOf NCIT_C1636 @default.
- NCIT_C71534 subClassOf NCIT_C1908 @default.
- NCIT_C71534 subClassOf NCIT_C1909 @default.
- NCIT_C71534 subClassOf NCIT_C211 @default.
- NCIT_C71534 subClassOf NCIT_C2364 @default.
- NCIT_C71534 subClassOf NCIT_C29712 @default.
- NCIT_C71534 subClassOf NCIT_C308 @default.
- NCIT_C71534 subClassOf NCIT_C319 @default.
- NCIT_C71534 subClassOf NCIT_C521 @default.
- NCIT_C71534 subClassOf NCIT_C548 @default.
- NCIT_C71534 subClassOf NCIT_C574 @default.
- NCIT_C71534 subClassOf NCIT_C71534 @default.
- NCIT_C71534 subClassOf NCIT_C78273 @default.