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- NCIT_C71536 IAO_0000115 "Autologous activated T cells, loaded with a bispecific antibody produced by heteroconjugation of anti-CD3 and anti-epidermal growth factor receptor (EGFR) monoclonal antibodies, with potential antineoplastic activity. Binding of EGFRBi-armed autologous activated T cells to EGFR-positive tumor cells may result in increased T cell-mediated cytotoxicity towards tumor cells expressing EGFR. Arming activated T cells with this bispecific antibody may significantly increase T cell secretion of anti-tumor associated cytokines such as IL2, RANTES, IFN-gamma, and TNF-alpha." @default.
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- NCIT_C71536 NCIT_P107 "EGFRBi-Armed Autologous T Cells" @default.
- NCIT_C71536 NCIT_P108 "EGFRBi-Armed Autologous T Cells" @default.
- NCIT_C71536 NCIT_P208 "CL378020" @default.
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- NCIT_C71536 NCIT_P329 "579877" @default.
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- NCIT_C71536 hasExactSynonym "EGFRBi-Armed Autologous T Cells" @default.
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- NCIT_C71536 type Class @default.
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- NCIT_C71536 label "EGFRBi-Armed Autologous T Cells" @default.
- NCIT_C71536 subClassOf NCIT_C129820 @default.
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