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- NCIT_C71633 IAO_0000115 "An orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation." @default.
- NCIT_C71633 NCIT_A32 NCIT_C1909 @default.
- NCIT_C71633 NCIT_A5 NCIT_C29367 @default.
- NCIT_C71633 NCIT_NHC0 "C71633" @default.
- NCIT_C71633 NCIT_P106 "Organic Chemical" @default.
- NCIT_C71633 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C71633 NCIT_P107 "Pioglitazone" @default.
- NCIT_C71633 NCIT_P108 "Pioglitazone" @default.
- NCIT_C71633 NCIT_P207 "C0071097" @default.
- NCIT_C71633 NCIT_P210 "111025-46-8" @default.
- NCIT_C71633 NCIT_P319 "X4OV71U42S" @default.
- NCIT_C71633 NCIT_P322 "CTRP" @default.
- NCIT_C71633 NCIT_P322 "FDA" @default.
- NCIT_C71633 NCIT_P322 "GDC" @default.
- NCIT_C71633 NCIT_P325 "A drug that is used to treat type 2 diabetes and is being studied in the prevention of head and neck cancer. It may be able to stop leukoplakia (a condition affecting the mouth) from developing into cancer. It is a type of thiazolidinedione." @default.
- NCIT_C71633 NCIT_P350 "C19H20N2O3S" @default.
- NCIT_C71633 NCIT_P366 "Pioglitazone_Base" @default.
- NCIT_C71633 NCIT_P368 "CHEBI:8228" @default.
- NCIT_C71633 NCIT_P375 "Pioglitazone" @default.
- NCIT_C71633 normalizedInformationContent "100" @default.
- NCIT_C71633 referenceCount "1" @default.
- NCIT_C71633 hasExactSynonym "PIOGLITAZONE" @default.
- NCIT_C71633 hasExactSynonym "Pioglitazone" @default.
- NCIT_C71633 hasExactSynonym "pioglitazone" @default.
- NCIT_C71633 inSubset NCIT_C116977 @default.
- NCIT_C71633 inSubset NCIT_C116978 @default.
- NCIT_C71633 inSubset NCIT_C128784 @default.
- NCIT_C71633 inSubset NCIT_C157711 @default.
- NCIT_C71633 inSubset NCIT_C157712 @default.
- NCIT_C71633 inSubset NCIT_C173381 @default.
- NCIT_C71633 inSubset NCIT_C173383 @default.
- NCIT_C71633 inSubset NCIT_C177537 @default.
- NCIT_C71633 inSubset NCIT_C63923 @default.
- NCIT_C71633 type Class @default.
- NCIT_C71633 isDefinedBy ncit.owl @default.
- NCIT_C71633 label "Pioglitazone" @default.
- NCIT_C71633 subClassOf NCIT_C1908 @default.
- NCIT_C71633 subClassOf NCIT_C1909 @default.
- NCIT_C71633 subClassOf NCIT_C29711 @default.
- NCIT_C71633 subClassOf NCIT_C71633 @default.
- NCIT_C71633 subClassOf NCIT_C78276 @default.
- NCIT_C71633 subClassOf NCIT_C98241 @default.