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- NCIT_C71693 IAO_0000115 "A fully human monoclonal antibody directed against human death receptor 5 (DR5; TRAIL-R2; TNFRSF10B) with potential pro-apoptotic and antineoplastic activities. Mimicking the natural ligand TRAIL (tumor necrosis factor-related apoptosis inducing ligand), apomab binds to DR5, which may directly activate the extrinsic apoptosis pathway and indirectly induce the intrinsic apoptosis pathway in tumor cells. DR5 is a cell surface receptor of the TNF-receptor superfamily and is expressed in a broad range of cancers." @default.
- NCIT_C71693 NCIT_A32 NCIT_C1909 @default.
- NCIT_C71693 NCIT_A7 NCIT_C18178 @default.
- NCIT_C71693 NCIT_NHC0 "C71693" @default.
- NCIT_C71693 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C71693 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C71693 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C71693 NCIT_P107 "Apomab" @default.
- NCIT_C71693 NCIT_P108 "Apomab" @default.
- NCIT_C71693 NCIT_P207 "C2346838" @default.
- NCIT_C71693 NCIT_P210 "1108170-71-3" @default.
- NCIT_C71693 NCIT_P319 "703KLX5LXZ" @default.
- NCIT_C71693 NCIT_P322 "CTRP" @default.
- NCIT_C71693 NCIT_P322 "FDA" @default.
- NCIT_C71693 NCIT_P322 "GDC" @default.
- NCIT_C71693 NCIT_P329 "555507" @default.
- NCIT_C71693 NCIT_P330 "555507" @default.
- NCIT_C71693 NCIT_P366 "Apomab" @default.
- NCIT_C71693 NCIT_P375 "Apomab" @default.
- NCIT_C71693 NCIT_P399 "555507" @default.
- NCIT_C71693 NCIT_R124 NCIT_C17710 @default.
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- NCIT_C71693 NCIT_R146 NCIT_C20027 @default.
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- NCIT_C71693 normalizedInformationContent "100" @default.
- NCIT_C71693 referenceCount "1" @default.
- NCIT_C71693 hasExactSynonym "APOMAB" @default.
- NCIT_C71693 hasExactSynonym "Apomab" @default.
- NCIT_C71693 inSubset NCIT_C116977 @default.
- NCIT_C71693 inSubset NCIT_C116978 @default.
- NCIT_C71693 inSubset NCIT_C128784 @default.
- NCIT_C71693 inSubset NCIT_C157711 @default.
- NCIT_C71693 inSubset NCIT_C157712 @default.
- NCIT_C71693 inSubset NCIT_C176424 @default.
- NCIT_C71693 inSubset NCIT_C177537 @default.
- NCIT_C71693 inSubset NCIT_C63923 @default.
- NCIT_C71693 type Class @default.
- NCIT_C71693 isDefinedBy ncit.owl @default.
- NCIT_C71693 label "Apomab" @default.
- NCIT_C71693 subClassOf B2473624c6015566096aa35fdd2a70a37 @default.
- NCIT_C71693 subClassOf B3da983d0b824b79a6e63b4c534709c61 @default.
- NCIT_C71693 subClassOf B76cbaca758cbf05cd15e7821dcec1298 @default.
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- NCIT_C71693 subClassOf NCIT_C1908 @default.
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- NCIT_C71693 subClassOf NCIT_C307 @default.
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- NCIT_C71693 subClassOf NCIT_C71693 @default.