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- NCIT_C72699 IAO_0000115 "The hydrochloride salt form of amotosalen, a synthetic psoralen and light-activated DNA, RNA crosslinking agent, with protective activity against pathogens such as bacteria, viruses, protozoa, and leukocytes. Prior to administration amotosalen is added to plasma and platelets, then in vivo the agent penetrates pathogens and targets DNA and RNA. Upon activation by ultraviolet A light, this agent is able to form interstrand DNA and RNA crosslinks and prevents replication. Inactivation of leukocytes can prevent graft versus host disease upon transfusion." @default.
- NCIT_C72699 NCIT_A6 NCIT_C76756 @default.
- NCIT_C72699 NCIT_NHC0 "C72699" @default.
- NCIT_C72699 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C72699 NCIT_P108 "Amotosalen Hydrochloride" @default.
- NCIT_C72699 NCIT_P207 "C2346748" @default.
- NCIT_C72699 NCIT_P210 "161262-45-9" @default.
- NCIT_C72699 NCIT_P319 "67B255SI5F" @default.
- NCIT_C72699 NCIT_P322 "FDA" @default.
- NCIT_C72699 NCIT_P350 "C17H19NO4.ClH" @default.
- NCIT_C72699 NCIT_P366 "Amotosalen_Hydrochloride" @default.
- NCIT_C72699 normalizedInformationContent "100" @default.
- NCIT_C72699 referenceCount "1" @default.
- NCIT_C72699 hasExactSynonym "AMOTOSALEN HYDROCHLORIDE" @default.
- NCIT_C72699 hasExactSynonym "Amotosalen Hydrochloride" @default.
- NCIT_C72699 inSubset NCIT_C63923 @default.
- NCIT_C72699 type Class @default.
- NCIT_C72699 isDefinedBy ncit.owl @default.
- NCIT_C72699 label "Amotosalen Hydrochloride" @default.
- NCIT_C72699 subClassOf NCIT_C186664 @default.
- NCIT_C72699 subClassOf NCIT_C1908 @default.
- NCIT_C72699 subClassOf NCIT_C1909 @default.
- NCIT_C72699 subClassOf NCIT_C2163 @default.
- NCIT_C72699 subClassOf NCIT_C25760 @default.
- NCIT_C72699 subClassOf NCIT_C274 @default.
- NCIT_C72699 subClassOf NCIT_C2842 @default.
- NCIT_C72699 subClassOf NCIT_C582 @default.
- NCIT_C72699 subClassOf NCIT_C72699 @default.