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- NCIT_C72706 IAO_0000115 "A broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Aspoxicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.
- NCIT_C72706 NCIT_NHC0 "C72706" @default.
- NCIT_C72706 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C72706 NCIT_P108 "Aspoxicillin" @default.
- NCIT_C72706 NCIT_P207 "C0104449" @default.
- NCIT_C72706 NCIT_P210 "63358-49-6" @default.
- NCIT_C72706 NCIT_P319 "0745KNO26J" @default.
- NCIT_C72706 NCIT_P322 "FDA" @default.
- NCIT_C72706 NCIT_P350 "C21H27N5O7S" @default.
- NCIT_C72706 NCIT_P366 "Aspoxicillin" @default.
- NCIT_C72706 normalizedInformationContent "100" @default.
- NCIT_C72706 referenceCount "1" @default.
- NCIT_C72706 hasExactSynonym "ASPOXICILLIN" @default.
- NCIT_C72706 hasExactSynonym "Aspoxicillin" @default.
- NCIT_C72706 inSubset NCIT_C63923 @default.
- NCIT_C72706 type Class @default.
- NCIT_C72706 isDefinedBy ncit.owl @default.
- NCIT_C72706 label "Aspoxicillin" @default.
- NCIT_C72706 subClassOf NCIT_C1500 @default.
- NCIT_C72706 subClassOf NCIT_C1908 @default.
- NCIT_C72706 subClassOf NCIT_C1909 @default.
- NCIT_C72706 subClassOf NCIT_C254 @default.
- NCIT_C72706 subClassOf NCIT_C258 @default.
- NCIT_C72706 subClassOf NCIT_C260 @default.
- NCIT_C72706 subClassOf NCIT_C72706 @default.