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- NCIT_C72912 IAO_0000115 "A potent angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Rentiapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Rentiapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.
- NCIT_C72912 NCIT_NHC0 "C72912" @default.
- NCIT_C72912 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C72912 NCIT_P108 "Rentiapril" @default.
- NCIT_C72912 NCIT_P207 "C0073061" @default.
- NCIT_C72912 NCIT_P210 "80830-42-8" @default.
- NCIT_C72912 NCIT_P319 "D0TAM1017B" @default.
- NCIT_C72912 NCIT_P322 "FDA" @default.
- NCIT_C72912 NCIT_P350 "C13H15NO4S2" @default.
- NCIT_C72912 NCIT_P366 "Rentiapril" @default.
- NCIT_C72912 normalizedInformationContent "100" @default.
- NCIT_C72912 referenceCount "1" @default.
- NCIT_C72912 hasExactSynonym "RENTIAPRIL" @default.
- NCIT_C72912 hasExactSynonym "Rentiapril" @default.
- NCIT_C72912 inSubset NCIT_C63923 @default.
- NCIT_C72912 type Class @default.
- NCIT_C72912 isDefinedBy ncit.owl @default.
- NCIT_C72912 label "Rentiapril" @default.
- NCIT_C72912 subClassOf NCIT_C1908 @default.
- NCIT_C72912 subClassOf NCIT_C1909 @default.
- NCIT_C72912 subClassOf NCIT_C247 @default.
- NCIT_C72912 subClassOf NCIT_C270 @default.
- NCIT_C72912 subClassOf NCIT_C471 @default.
- NCIT_C72912 subClassOf NCIT_C72912 @default.
- NCIT_C72912 subClassOf NCIT_C78274 @default.
- NCIT_C72912 subClassOf NCIT_C783 @default.