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- NCIT_C72914 IAO_0000115 "A thiadiazoline angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Utibaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Utibaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.
- NCIT_C72914 NCIT_NHC0 "C72914" @default.
- NCIT_C72914 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C72914 NCIT_P108 "Utibaprilat" @default.
- NCIT_C72914 NCIT_P207 "C0950771" @default.
- NCIT_C72914 NCIT_P210 "109683-79-6" @default.
- NCIT_C72914 NCIT_P319 "KN82541NHV" @default.
- NCIT_C72914 NCIT_P322 "FDA" @default.
- NCIT_C72914 NCIT_P350 "C20H27N3O5S" @default.
- NCIT_C72914 NCIT_P366 "Utibaprilat" @default.
- NCIT_C72914 normalizedInformationContent "100" @default.
- NCIT_C72914 referenceCount "1" @default.
- NCIT_C72914 hasExactSynonym "FPL 63547" @default.
- NCIT_C72914 hasExactSynonym "UTIBAPRILAT" @default.
- NCIT_C72914 hasExactSynonym "Utibaprilat" @default.
- NCIT_C72914 inSubset NCIT_C63923 @default.
- NCIT_C72914 type Class @default.
- NCIT_C72914 isDefinedBy ncit.owl @default.
- NCIT_C72914 label "Utibaprilat" @default.
- NCIT_C72914 subClassOf NCIT_C1908 @default.
- NCIT_C72914 subClassOf NCIT_C1909 @default.
- NCIT_C72914 subClassOf NCIT_C247 @default.
- NCIT_C72914 subClassOf NCIT_C270 @default.
- NCIT_C72914 subClassOf NCIT_C471 @default.
- NCIT_C72914 subClassOf NCIT_C72914 @default.
- NCIT_C72914 subClassOf NCIT_C78274 @default.
- NCIT_C72914 subClassOf NCIT_C783 @default.