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- NCIT_C731 IAO_0000115 "A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it appears to interact directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. (NCI04)" @default.
- NCIT_C731 NCIT_A5 NCIT_C29349 @default.
- NCIT_C731 NCIT_NHC0 "C731" @default.
- NCIT_C731 NCIT_P106 "Antibiotic" @default.
- NCIT_C731 NCIT_P106 "Organic Chemical" @default.
- NCIT_C731 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C731 NCIT_P107 "Pentamidine" @default.
- NCIT_C731 NCIT_P108 "Pentamidine" @default.
- NCIT_C731 NCIT_P175 "9921" @default.
- NCIT_C731 NCIT_P207 "C0030863" @default.
- NCIT_C731 NCIT_P210 "100-33-4" @default.
- NCIT_C731 NCIT_P319 "673LC5J4LQ" @default.
- NCIT_C731 NCIT_P322 "CTRP" @default.
- NCIT_C731 NCIT_P322 "FDA" @default.
- NCIT_C731 NCIT_P325 "The active ingredient in a drug used to treat infections caused by certain microorganisms. It is also being studied in the treatment of melanoma. It prevents DNA from being copied and may kill cancer cells. It is a type of antifungal agent, a type of antiprotozoal agent, and a type of PRL phosphatase inhibitor." @default.
- NCIT_C731 NCIT_P329 "40324" @default.
- NCIT_C731 NCIT_P330 "40324" @default.
- NCIT_C731 NCIT_P350 "C19H24N4O2" @default.
- NCIT_C731 NCIT_P366 "Pentamidine" @default.
- NCIT_C731 NCIT_P368 "CHEBI:45081" @default.
- NCIT_C731 NCIT_P399 "40324" @default.
- NCIT_C731 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C731 referenceCount "3" @default.
- NCIT_C731 hasExactSynonym "Aerosolized Pentamadine" @default.
- NCIT_C731 hasExactSynonym "PENTAMIDINE" @default.
- NCIT_C731 hasExactSynonym "Pentamidine" @default.
- NCIT_C731 hasExactSynonym "pentamidine" @default.
- NCIT_C731 inSubset NCIT_C116977 @default.
- NCIT_C731 inSubset NCIT_C116978 @default.
- NCIT_C731 inSubset NCIT_C176424 @default.
- NCIT_C731 inSubset NCIT_C63923 @default.
- NCIT_C731 type Class @default.
- NCIT_C731 isDefinedBy ncit.owl @default.
- NCIT_C731 label "Pentamidine" @default.
- NCIT_C731 subClassOf NCIT_C1908 @default.
- NCIT_C731 subClassOf NCIT_C1909 @default.
- NCIT_C731 subClassOf NCIT_C254 @default.
- NCIT_C731 subClassOf NCIT_C276 @default.
- NCIT_C731 subClassOf NCIT_C277 @default.
- NCIT_C731 subClassOf NCIT_C514 @default.
- NCIT_C731 subClassOf NCIT_C731 @default.