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- NCIT_C73685 IAO_0000115 "Chromobox protein homolog 5 (191 aa, ~22 kDa) is encoded by the human CBX5 gene. This soluble, nuclear protein plays a role in epigenetic modification of chromatin, by catalyzing the monomethylation of lysine 5 of histone H2B. The outcome of this modification is associated with either activated gene transcription, or, if further processed to trimethylated lysine 5, epigenetically repressed gene transcription. By affecting the balance of chromatin in heterochromatin and euchromatin at specific gene loci, this protein acts as a candidate tumor suppressor." @default.
- NCIT_C73685 NCIT_NHC0 "C73685" @default.
- NCIT_C73685 NCIT_P100 "604478" @default.
- NCIT_C73685 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C73685 NCIT_P108 "Chromobox Protein Homolog 5" @default.
- NCIT_C73685 NCIT_P207 "C2347769" @default.
- NCIT_C73685 NCIT_P366 "Chromobox_Protein_Homolog_5" @default.
- NCIT_C73685 NCIT_P93 "P45973" @default.
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- NCIT_C73685 referenceCount "1" @default.
- NCIT_C73685 hasExactSynonym "Antigen p25" @default.
- NCIT_C73685 hasExactSynonym "CBX5" @default.
- NCIT_C73685 hasExactSynonym "Chromobox Protein Homolog 5" @default.
- NCIT_C73685 hasExactSynonym "HP1 Alpha" @default.
- NCIT_C73685 hasExactSynonym "HP1 alpha" @default.
- NCIT_C73685 hasExactSynonym "Heterochromatin protein 1 homolog alpha" @default.
- NCIT_C73685 type Class @default.
- NCIT_C73685 isDefinedBy ncit.owl @default.
- NCIT_C73685 label "Chromobox Protein Homolog 5" @default.
- NCIT_C73685 subClassOf NCIT_C17021 @default.
- NCIT_C73685 subClassOf NCIT_C18466 @default.
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- NCIT_C73685 equivalentClass B9592c1d57362276805df47bef51f57b0 @default.