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- NCIT_C73835 IAO_0000115 "The pamoate salt form of a semisynthetic, orally active pivalate ester of ampicillin with antibacterial activity. Upon absorption, pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.
- NCIT_C73835 NCIT_A6 NCIT_C84068 @default.
- NCIT_C73835 NCIT_NHC0 "C73835" @default.
- NCIT_C73835 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C73835 NCIT_P108 "Pivampicillin Pamoate" @default.
- NCIT_C73835 NCIT_P207 "C2347522" @default.
- NCIT_C73835 NCIT_P210 "39030-72-3" @default.
- NCIT_C73835 NCIT_P319 "5Z5TRG74EY" @default.
- NCIT_C73835 NCIT_P322 "FDA" @default.
- NCIT_C73835 NCIT_P350 "C23H16O6.2C22H29N3O6S" @default.
- NCIT_C73835 NCIT_P366 "Pivampicillin_Pamoate" @default.
- NCIT_C73835 normalizedInformationContent "100" @default.
- NCIT_C73835 referenceCount "1" @default.
- NCIT_C73835 hasExactSynonym "PIVAMPICILLIN PAMOATE" @default.
- NCIT_C73835 hasExactSynonym "Pivampicillin Pamoate" @default.
- NCIT_C73835 inSubset NCIT_C63923 @default.
- NCIT_C73835 type Class @default.
- NCIT_C73835 isDefinedBy ncit.owl @default.
- NCIT_C73835 label "Pivampicillin Pamoate" @default.
- NCIT_C73835 subClassOf NCIT_C1500 @default.
- NCIT_C73835 subClassOf NCIT_C1908 @default.
- NCIT_C73835 subClassOf NCIT_C1909 @default.
- NCIT_C73835 subClassOf NCIT_C254 @default.
- NCIT_C73835 subClassOf NCIT_C258 @default.
- NCIT_C73835 subClassOf NCIT_C260 @default.
- NCIT_C73835 subClassOf NCIT_C73835 @default.