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- NCIT_C73839 IAO_0000115 "The hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Revaprazan concentrates highly in the gastric parietal cell canaliculus and on entering this acidic environment is instantly protonated and binds competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production." @default.
- NCIT_C73839 NCIT_A6 NCIT_C76489 @default.
- NCIT_C73839 NCIT_NHC0 "C73839" @default.
- NCIT_C73839 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C73839 NCIT_P108 "Revaprazan Hydrochloride" @default.
- NCIT_C73839 NCIT_P207 "C2347960" @default.
- NCIT_C73839 NCIT_P210 "178307-42-1" @default.
- NCIT_C73839 NCIT_P319 "4DQ6T10R64" @default.
- NCIT_C73839 NCIT_P322 "FDA" @default.
- NCIT_C73839 NCIT_P350 "C22H23FN4.HCl" @default.
- NCIT_C73839 NCIT_P366 "Revaprazan_Hydrochloride" @default.
- NCIT_C73839 normalizedInformationContent "100" @default.
- NCIT_C73839 referenceCount "1" @default.
- NCIT_C73839 hasExactSynonym "REVAPRAZAN HYDROCHLORIDE" @default.
- NCIT_C73839 hasExactSynonym "Revaprazan Hydrochloride" @default.
- NCIT_C73839 inSubset NCIT_C63923 @default.
- NCIT_C73839 type Class @default.
- NCIT_C73839 isDefinedBy ncit.owl @default.
- NCIT_C73839 label "Revaprazan Hydrochloride" @default.
- NCIT_C73839 subClassOf NCIT_C1908 @default.
- NCIT_C73839 subClassOf NCIT_C1909 @default.
- NCIT_C73839 subClassOf NCIT_C29701 @default.
- NCIT_C73839 subClassOf NCIT_C29723 @default.
- NCIT_C73839 subClassOf NCIT_C73839 @default.
- NCIT_C73839 subClassOf NCIT_C78276 @default.