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- NCIT_C740 IAO_0000115 "A class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain, potentially preventing chemotherapy-induced emesis. In addition, these agents have peripherally or centrally antagonistic activity against alpha adrenergic, serotonergic, histaminic, and muscarinic receptors. (NCI)" @default.
- NCIT_C740 NCIT_NHC0 "C740" @default.
- NCIT_C740 NCIT_P106 "Organic Chemical" @default.
- NCIT_C740 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C740 NCIT_P108 "Phenothiazine" @default.
- NCIT_C740 NCIT_P207 "C0031436" @default.
- NCIT_C740 NCIT_P210 "92-84-2" @default.
- NCIT_C740 NCIT_P319 "GS9EX7QNU6" @default.
- NCIT_C740 NCIT_P322 "FDA" @default.
- NCIT_C740 NCIT_P325 "A type of drug that is used to treat severe mental and emotional disorders, severe nausea and vomiting, and certain other conditions. It belongs to the families of drugs called antipsychotics and antiemetics." @default.
- NCIT_C740 NCIT_P350 "C12H9NS" @default.
- NCIT_C740 NCIT_P366 "Phenothiazine" @default.
- NCIT_C740 NCIT_P368 "CHEBI:37931" @default.
- NCIT_C740 NCIT_P368 "CHEBI:38093" @default.
- NCIT_C740 normalizedInformationContent "76.473685442280228" @default.
- NCIT_C740 referenceCount "35" @default.
- NCIT_C740 hasExactSynonym "PHENOTHIAZINE" @default.
- NCIT_C740 hasExactSynonym "Phenothiazine" @default.
- NCIT_C740 hasExactSynonym "phenothiazine" @default.
- NCIT_C740 inSubset NCIT_C63923 @default.
- NCIT_C740 type Class @default.
- NCIT_C740 isDefinedBy ncit.owl @default.
- NCIT_C740 label "Phenothiazine" @default.
- NCIT_C740 subClassOf NCIT_C1908 @default.
- NCIT_C740 subClassOf NCIT_C1909 @default.
- NCIT_C740 subClassOf NCIT_C267 @default.
- NCIT_C740 subClassOf NCIT_C740 @default.
- NCIT_C740 subClassOf NCIT_C78272 @default.