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- NCIT_C74000 IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells loaded with separate preparations of acute myelogenous leukemia (AML) cell lysate and AML-specific messenger RNA (mRNA) with potential immunostimulatory and antineoplastic activities. Upon administration, AML mRNA plus lysate loaded autologous dendritic cell vaccine may elicit a potent cytotoxic T-cell (CTL) response against AML cells, resulting in tumor cell death. Autologous dendritic cells doubly-loaded with AML cell lysate and AML-specific mRNA may elicit superior primary, recall, and effector lytic immune responses compared to autologous dendritic cells loaded with tumor lysate or tumor mRNA alone." @default.
- NCIT_C74000 NCIT_NHC0 "C74000" @default.
- NCIT_C74000 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74000 NCIT_P108 "AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C74000 NCIT_P208 "CL383547" @default.
- NCIT_C74000 NCIT_P329 "590709" @default.
- NCIT_C74000 NCIT_P330 "590709" @default.
- NCIT_C74000 NCIT_P366 "AML_mRNA_Positive_Lysate_Loaded_Autologous_Dendritic_Cell_Vaccine" @default.
- NCIT_C74000 NCIT_P399 "590709" @default.
- NCIT_C74000 normalizedInformationContent "100" @default.
- NCIT_C74000 referenceCount "1" @default.
- NCIT_C74000 hasExactSynonym "AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C74000 hasExactSynonym "Acute Myelogenous Leukemia mRNA Plus Lysate Loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C74000 inSubset NCIT_C128784 @default.
- NCIT_C74000 inSubset NCIT_C176424 @default.
- NCIT_C74000 type Class @default.
- NCIT_C74000 isDefinedBy ncit.owl @default.
- NCIT_C74000 label "AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine" @default.
- NCIT_C74000 subClassOf NCIT_C129820 @default.
- NCIT_C74000 subClassOf NCIT_C1663 @default.
- NCIT_C74000 subClassOf NCIT_C172787 @default.
- NCIT_C74000 subClassOf NCIT_C181141 @default.
- NCIT_C74000 subClassOf NCIT_C1908 @default.
- NCIT_C74000 subClassOf NCIT_C1909 @default.
- NCIT_C74000 subClassOf NCIT_C274 @default.
- NCIT_C74000 subClassOf NCIT_C28308 @default.
- NCIT_C74000 subClassOf NCIT_C28310 @default.
- NCIT_C74000 subClassOf NCIT_C307 @default.
- NCIT_C74000 subClassOf NCIT_C308 @default.
- NCIT_C74000 subClassOf NCIT_C74000 @default.
- NCIT_C74000 subClassOf NCIT_C923 @default.