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- NCIT_C74021 IAO_0000115 "An orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis." @default.
- NCIT_C74021 NCIT_A32 NCIT_C1909 @default.
- NCIT_C74021 NCIT_A7 NCIT_C17984 @default.
- NCIT_C74021 NCIT_NHC0 "C74021" @default.
- NCIT_C74021 NCIT_P106 "Organic Chemical" @default.
- NCIT_C74021 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74021 NCIT_P107 "Apricoxib" @default.
- NCIT_C74021 NCIT_P108 "Apricoxib" @default.
- NCIT_C74021 NCIT_P207 "C1737955" @default.
- NCIT_C74021 NCIT_P210 "197904-84-0" @default.
- NCIT_C74021 NCIT_P319 "5X5HB3VZ3Z" @default.
- NCIT_C74021 NCIT_P322 "CTRP" @default.
- NCIT_C74021 NCIT_P322 "FDA" @default.
- NCIT_C74021 NCIT_P322 "GDC" @default.
- NCIT_C74021 NCIT_P329 "594363" @default.
- NCIT_C74021 NCIT_P330 "594363" @default.
- NCIT_C74021 NCIT_P350 "C19H20N2O3S" @default.
- NCIT_C74021 NCIT_P366 "COX-2_Inhibitor_TG01" @default.
- NCIT_C74021 NCIT_P375 "Apricoxib" @default.
- NCIT_C74021 NCIT_P399 "594363" @default.
- NCIT_C74021 normalizedInformationContent "100" @default.
- NCIT_C74021 referenceCount "1" @default.
- NCIT_C74021 hasExactSynonym "APRICOXIB" @default.
- NCIT_C74021 hasExactSynonym "Apricoxib" @default.
- NCIT_C74021 hasExactSynonym "COX-2 Inhibitor TG01" @default.
- NCIT_C74021 hasExactSynonym "CS-706" @default.
- NCIT_C74021 hasExactSynonym "R-109339" @default.
- NCIT_C74021 hasExactSynonym "TG01" @default.
- NCIT_C74021 hasExactSynonym "TP2001" @default.
- NCIT_C74021 inSubset NCIT_C116977 @default.
- NCIT_C74021 inSubset NCIT_C116978 @default.
- NCIT_C74021 inSubset NCIT_C128784 @default.
- NCIT_C74021 inSubset NCIT_C157711 @default.
- NCIT_C74021 inSubset NCIT_C157712 @default.
- NCIT_C74021 inSubset NCIT_C176424 @default.
- NCIT_C74021 inSubset NCIT_C177537 @default.
- NCIT_C74021 inSubset NCIT_C63923 @default.
- NCIT_C74021 type Class @default.
- NCIT_C74021 isDefinedBy ncit.owl @default.
- NCIT_C74021 label "Apricoxib" @default.
- NCIT_C74021 subClassOf NCIT_C1323 @default.
- NCIT_C74021 subClassOf NCIT_C1742 @default.
- NCIT_C74021 subClassOf NCIT_C1908 @default.
- NCIT_C74021 subClassOf NCIT_C1909 @default.
- NCIT_C74021 subClassOf NCIT_C2198 @default.
- NCIT_C74021 subClassOf NCIT_C2356 @default.
- NCIT_C74021 subClassOf NCIT_C241 @default.
- NCIT_C74021 subClassOf NCIT_C257 @default.
- NCIT_C74021 subClassOf NCIT_C274 @default.
- NCIT_C74021 subClassOf NCIT_C471 @default.
- NCIT_C74021 subClassOf NCIT_C74021 @default.
- NCIT_C74021 subClassOf NCIT_C78272 @default.
- NCIT_C74021 subClassOf NCIT_C80509 @default.