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- NCIT_C74035 IAO_0000115 "A cancer vaccine, containing epitopes of the gangliosides GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with GD2 lactone/GD3 lactone-KLH conjugate bivalent vaccine may elicit antibodies against tumor cells expressing either epitope, resulting in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC). Located primarily in the nervous system, gangliosides, such as GD2 and GD3, are cell membrane components involved in cellular recognition and cell-cell communication." @default.
- NCIT_C74035 NCIT_A7 NCIT_C1110 @default.
- NCIT_C74035 NCIT_A7 NCIT_C39782 @default.
- NCIT_C74035 NCIT_NHC0 "C74035" @default.
- NCIT_C74035 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74035 NCIT_P107 "GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine" @default.
- NCIT_C74035 NCIT_P108 "GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine" @default.
- NCIT_C74035 NCIT_P208 "CL383507" @default.
- NCIT_C74035 NCIT_P322 "CTRP" @default.
- NCIT_C74035 NCIT_P329 "588002" @default.
- NCIT_C74035 NCIT_P330 "588002" @default.
- NCIT_C74035 NCIT_P366 "GD2_Lactone_GD3_Lactone-KLH_Conjugate_Bivalent_Vaccine" @default.
- NCIT_C74035 NCIT_P399 "588002" @default.
- NCIT_C74035 normalizedInformationContent "100" @default.
- NCIT_C74035 referenceCount "1" @default.
- NCIT_C74035 hasExactSynonym "GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine" @default.
- NCIT_C74035 inSubset NCIT_C116977 @default.
- NCIT_C74035 inSubset NCIT_C116978 @default.
- NCIT_C74035 inSubset NCIT_C128784 @default.
- NCIT_C74035 inSubset NCIT_C176424 @default.
- NCIT_C74035 type Class @default.
- NCIT_C74035 isDefinedBy ncit.owl @default.
- NCIT_C74035 label "GD2 Lactone/GD3 Lactone-KLH Conjugate Bivalent Vaccine" @default.
- NCIT_C74035 subClassOf NCIT_C129820 @default.
- NCIT_C74035 subClassOf NCIT_C1663 @default.
- NCIT_C74035 subClassOf NCIT_C1908 @default.
- NCIT_C74035 subClassOf NCIT_C1909 @default.
- NCIT_C74035 subClassOf NCIT_C274 @default.
- NCIT_C74035 subClassOf NCIT_C307 @default.
- NCIT_C74035 subClassOf NCIT_C308 @default.
- NCIT_C74035 subClassOf NCIT_C74035 @default.
- NCIT_C74035 subClassOf NCIT_C923 @default.