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- NCIT_C74084 IAO_0000115 "A proprietary oligonucleotide with immunostimulatory activity. Immunostimulatory phosphorothiolate oligodeoxyribonucleotide SD-101 targets Toll-Like Receptor 9 (TLR9) found on a specialized subset of dendritic cells. The interaction of TLR9 with SD-101, in conjunction with an allergen or antigen, induces activation of memory T helper cells 1 (Th1) against a specific pathogen or allergen, thereby leading to long-lasting therapeutic effects. Furthermore, this agent does not cause a generalized activation of the immune system." @default.
- NCIT_C74084 NCIT_A32 NCIT_C1909 @default.
- NCIT_C74084 NCIT_A7 NCIT_C96048 @default.
- NCIT_C74084 NCIT_NHC0 "C74084" @default.
- NCIT_C74084 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74084 NCIT_P107 "TLR9 Agonist SD-101" @default.
- NCIT_C74084 NCIT_P108 "TLR9 Agonist SD-101" @default.
- NCIT_C74084 NCIT_P207 "C2348637" @default.
- NCIT_C74084 NCIT_P322 "CTRP" @default.
- NCIT_C74084 NCIT_P322 "GDC" @default.
- NCIT_C74084 NCIT_P329 "706877" @default.
- NCIT_C74084 NCIT_P330 "706877" @default.
- NCIT_C74084 NCIT_P366 "TLR9_Agonist_SD-101" @default.
- NCIT_C74084 NCIT_P375 "TLR9 Agonist SD-101" @default.
- NCIT_C74084 NCIT_P399 "706877" @default.
- NCIT_C74084 normalizedInformationContent "100" @default.
- NCIT_C74084 referenceCount "1" @default.
- NCIT_C74084 hasExactSynonym "ISS-ODN SD-101" @default.
- NCIT_C74084 hasExactSynonym "SD-101" @default.
- NCIT_C74084 hasExactSynonym "TLR9 Agonist SD-101" @default.
- NCIT_C74084 inSubset NCIT_C116977 @default.
- NCIT_C74084 inSubset NCIT_C116978 @default.
- NCIT_C74084 inSubset NCIT_C157711 @default.
- NCIT_C74084 inSubset NCIT_C157712 @default.
- NCIT_C74084 inSubset NCIT_C176424 @default.
- NCIT_C74084 inSubset NCIT_C177537 @default.
- NCIT_C74084 type Class @default.
- NCIT_C74084 isDefinedBy ncit.owl @default.
- NCIT_C74084 label "TLR9 Agonist SD-101" @default.
- NCIT_C74084 subClassOf NCIT_C177174 @default.
- NCIT_C74084 subClassOf NCIT_C177175 @default.
- NCIT_C74084 subClassOf NCIT_C1908 @default.
- NCIT_C74084 subClassOf NCIT_C1909 @default.
- NCIT_C74084 subClassOf NCIT_C1962 @default.
- NCIT_C74084 subClassOf NCIT_C2139 @default.
- NCIT_C74084 subClassOf NCIT_C307 @default.
- NCIT_C74084 subClassOf NCIT_C308 @default.
- NCIT_C74084 subClassOf NCIT_C74084 @default.