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- NCIT_C74138 IAO_0000115 "A competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo into its active metabolite 5-hydroxy methyl tolterodine, which binds and inhibits muscarinic receptors on the bladder detrusor muscle, thereby preventing bladder contractions or spasms caused by acetylcholine. This results in the relaxation of bladder smooth muscle and greater bladder capacity, in addition to a reduction in involuntary muscle contractions and involuntary loss of urine. The active metabolite does not interact with alpha-adrenergic, serotonergic, histaminergic and excitatory amino acid receptors and is eliminated via renal excretion." @default.
- NCIT_C74138 NCIT_A5 NCIT_C72779 @default.
- NCIT_C74138 NCIT_NHC0 "C74138" @default.
- NCIT_C74138 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74138 NCIT_P108 "Fesoterodine" @default.
- NCIT_C74138 NCIT_P207 "C2343853" @default.
- NCIT_C74138 NCIT_P210 "286930-02-7" @default.
- NCIT_C74138 NCIT_P319 "621G617227" @default.
- NCIT_C74138 NCIT_P322 "FDA" @default.
- NCIT_C74138 NCIT_P350 "C26H37NO3" @default.
- NCIT_C74138 NCIT_P366 "Fesoterodine" @default.
- NCIT_C74138 normalizedInformationContent "100" @default.
- NCIT_C74138 referenceCount "1" @default.
- NCIT_C74138 hasExactSynonym "FESOTERODINE" @default.
- NCIT_C74138 hasExactSynonym "Fesoterodine" @default.
- NCIT_C74138 hasExactSynonym "Propanoic acid, 2-methyl-, 2-((1R)-3-(bis(1-methylethyl)amino)-1-phenylpropyl)-4-(hydroxymethyl)phenyl Ester" @default.
- NCIT_C74138 inSubset NCIT_C63923 @default.
- NCIT_C74138 type Class @default.
- NCIT_C74138 isDefinedBy ncit.owl @default.
- NCIT_C74138 label "Fesoterodine" @default.
- NCIT_C74138 subClassOf NCIT_C1908 @default.
- NCIT_C74138 subClassOf NCIT_C1909 @default.
- NCIT_C74138 subClassOf NCIT_C29704 @default.
- NCIT_C74138 subClassOf NCIT_C66880 @default.
- NCIT_C74138 subClassOf NCIT_C74138 @default.
- NCIT_C74138 subClassOf NCIT_C78272 @default.