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- NCIT_C74354 IAO_0000115 "An orally available phosphodiesterase type 5 (PDE5) inhibitor with vasodilatory activity. Avanafil selectively inhibits PDE5, thus inhibiting the degradation of cyclic guanosine monophosphate (cGMP) found in the smooth muscle of the corpus cavernosa of the penis. The inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, thereby prolonging penile erection." @default.
- NCIT_C74354 NCIT_NHC0 "C74354" @default.
- NCIT_C74354 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74354 NCIT_P107 "Avanafil" @default.
- NCIT_C74354 NCIT_P108 "Avanafil" @default.
- NCIT_C74354 NCIT_P207 "C2698280" @default.
- NCIT_C74354 NCIT_P210 "330784-47-9" @default.
- NCIT_C74354 NCIT_P319 "DR5S136IVO" @default.
- NCIT_C74354 NCIT_P322 "CTRP" @default.
- NCIT_C74354 NCIT_P322 "FDA" @default.
- NCIT_C74354 NCIT_P329 "683134" @default.
- NCIT_C74354 NCIT_P330 "683134" @default.
- NCIT_C74354 NCIT_P350 "C23H26ClN7O3" @default.
- NCIT_C74354 NCIT_P366 "Avanafil" @default.
- NCIT_C74354 NCIT_P399 "683134" @default.
- NCIT_C74354 normalizedInformationContent "100" @default.
- NCIT_C74354 referenceCount "1" @default.
- NCIT_C74354 hasExactSynonym "(S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamide" @default.
- NCIT_C74354 hasExactSynonym "AVANAFIL" @default.
- NCIT_C74354 hasExactSynonym "Avanafil" @default.
- NCIT_C74354 hasExactSynonym "Stendra" @default.
- NCIT_C74354 hasExactSynonym "TA 1790" @default.
- NCIT_C74354 hasExactSynonym "TA-1790" @default.
- NCIT_C74354 inSubset NCIT_C116977 @default.
- NCIT_C74354 inSubset NCIT_C116978 @default.
- NCIT_C74354 inSubset NCIT_C176424 @default.
- NCIT_C74354 inSubset NCIT_C63923 @default.
- NCIT_C74354 type Class @default.
- NCIT_C74354 isDefinedBy ncit.owl @default.
- NCIT_C74354 label "Avanafil" @default.
- NCIT_C74354 subClassOf NCIT_C1908 @default.
- NCIT_C74354 subClassOf NCIT_C1909 @default.
- NCIT_C74354 subClassOf NCIT_C2127 @default.
- NCIT_C74354 subClassOf NCIT_C471 @default.
- NCIT_C74354 subClassOf NCIT_C74354 @default.
- NCIT_C74354 subClassOf NCIT_C744 @default.