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- NCIT_C74595 IAO_0000115 "A cancer vaccine containing a live-attenuated strain of the bacterium Listeria monocytogenes (Lm) encoding human papillomavirus (HPV) type 16 E7 fused to a non-hemolytic listeriolysin O protein with potential immunostimulatory and antineoplastic activities. Upon vaccination with axalimogene filolisbac, Listeria expresses the HPV 16 E7 antigen and activates the immune system to mount a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing HPV 16 E7. This may result in tumor cell lysis. In addition, the Listeria vector itself may induce a potent immune response. HPV 16 E7, a cell surface glycoprotein and tumor associated antigen, is overexpressed in the majority of cervical cancer cells." @default.
- NCIT_C74595 NCIT_A32 NCIT_C1909 @default.
- NCIT_C74595 NCIT_A7 NCIT_C1179 @default.
- NCIT_C74595 NCIT_NHC0 "C74595" @default.
- NCIT_C74595 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C74595 NCIT_P107 "Axalimogene Filolisbac" @default.
- NCIT_C74595 NCIT_P108 "Axalimogene Filolisbac" @default.
- NCIT_C74595 NCIT_P208 "CL384120" @default.
- NCIT_C74595 NCIT_P210 "1587258-09-0" @default.
- NCIT_C74595 NCIT_P319 "NY7PTD1862" @default.
- NCIT_C74595 NCIT_P322 "CTRP" @default.
- NCIT_C74595 NCIT_P322 "FDA" @default.
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- NCIT_C74595 NCIT_P329 "673240" @default.
- NCIT_C74595 NCIT_P330 "673240" @default.
- NCIT_C74595 NCIT_P366 "Attenuated_Live_Listeria_Encoding_HPV_16_E7_Vaccine" @default.
- NCIT_C74595 NCIT_P375 "Attenuated Live Listeria Encoding HPV 16 E7 Vaccine ADXS11-001" @default.
- NCIT_C74595 NCIT_P375 "Axalimogene Filolisbac" @default.
- NCIT_C74595 NCIT_P399 "673240" @default.
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- NCIT_C74595 NCIT_R72 NCIT_C32725 @default.
- NCIT_C74595 NCIT_R72 NCIT_C33061 @default.
- NCIT_C74595 NCIT_R72 NCIT_C38434 @default.
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- NCIT_C74595 NCIT_R72 NCIT_C39567 @default.
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- NCIT_C74595 normalizedInformationContent "100" @default.
- NCIT_C74595 referenceCount "1" @default.
- NCIT_C74595 hasExactSynonym "ADXS11-001 Vaccine" @default.
- NCIT_C74595 hasExactSynonym "ADXS11-001" @default.
- NCIT_C74595 hasExactSynonym "AXALIMOGENE FILOLISBAC" @default.
- NCIT_C74595 hasExactSynonym "Attenuated Live Listeria Encoding HPV 16 E7 Vaccine" @default.
- NCIT_C74595 hasExactSynonym "Attenuated Live Listeria Encoding Human Papilloma Virus 16 E7 Vaccine" @default.
- NCIT_C74595 hasExactSynonym "Axalimogene Filolisbac" @default.
- NCIT_C74595 hasExactSynonym "Lm-LLO-E7" @default.
- NCIT_C74595 hasExactSynonym "Lovaxin-C" @default.
- NCIT_C74595 inSubset NCIT_C116977 @default.
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- NCIT_C74595 type Class @default.
- NCIT_C74595 isDefinedBy ncit.owl @default.
- NCIT_C74595 label "Axalimogene Filolisbac" @default.
- NCIT_C74595 subClassOf B1fb5dd030504b8560c6562b7b49e3ed7 @default.
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