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- NCIT_C75124 IAO_0000115 "A 9-aza-anthrapyrazole antineoplastic antibiotic. Topixantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Compared to other DNA intercalators, this agent shows minimal cardiotoxicity." @default.
- NCIT_C75124 NCIT_A32 NCIT_C1909 @default.
- NCIT_C75124 NCIT_NHC0 "C75124" @default.
- NCIT_C75124 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C75124 NCIT_P108 "Topixantrone" @default.
- NCIT_C75124 NCIT_P207 "C1528075" @default.
- NCIT_C75124 NCIT_P210 "156090-18-5" @default.
- NCIT_C75124 NCIT_P319 "R40RXC296C" @default.
- NCIT_C75124 NCIT_P322 "FDA" @default.
- NCIT_C75124 NCIT_P322 "GDC" @default.
- NCIT_C75124 NCIT_P350 "C21H26N6O2" @default.
- NCIT_C75124 NCIT_P366 "Topixantrone" @default.
- NCIT_C75124 NCIT_P375 "Topixantrone" @default.
- NCIT_C75124 normalizedInformationContent "100" @default.
- NCIT_C75124 referenceCount "1" @default.
- NCIT_C75124 hasExactSynonym "BBR 3576" @default.
- NCIT_C75124 hasExactSynonym "Indazolo(4,3-gh)isoquinolin-6(2H)-one, 5-((2-(dimethylamino)ethyl)amino)-2-(2-((2-hydroxyethyl)amino)ethyl)-" @default.
- NCIT_C75124 hasExactSynonym "TOPIXANTRONE" @default.
- NCIT_C75124 hasExactSynonym "Topixantrone" @default.
- NCIT_C75124 inSubset NCIT_C128784 @default.
- NCIT_C75124 inSubset NCIT_C157711 @default.
- NCIT_C75124 inSubset NCIT_C157712 @default.
- NCIT_C75124 inSubset NCIT_C177537 @default.
- NCIT_C75124 inSubset NCIT_C63923 @default.
- NCIT_C75124 type Class @default.
- NCIT_C75124 isDefinedBy ncit.owl @default.
- NCIT_C75124 label "Topixantrone" @default.
- NCIT_C75124 subClassOf NCIT_C186664 @default.
- NCIT_C75124 subClassOf NCIT_C1908 @default.
- NCIT_C75124 subClassOf NCIT_C1909 @default.
- NCIT_C75124 subClassOf NCIT_C2107 @default.
- NCIT_C75124 subClassOf NCIT_C274 @default.
- NCIT_C75124 subClassOf NCIT_C2842 @default.
- NCIT_C75124 subClassOf NCIT_C582 @default.
- NCIT_C75124 subClassOf NCIT_C75124 @default.