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- NCIT_C76135 IAO_0000115 "The anhydrous form of enalaprilat, a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow." @default.
- NCIT_C76135 NCIT_NHC0 "C76135" @default.
- NCIT_C76135 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C76135 NCIT_P108 "Enalaprilat Anhydrous" @default.
- NCIT_C76135 NCIT_P207 "C0886809" @default.
- NCIT_C76135 NCIT_P210 "76420-72-9" @default.
- NCIT_C76135 NCIT_P319 "Q508Q118JM" @default.
- NCIT_C76135 NCIT_P322 "FDA" @default.
- NCIT_C76135 NCIT_P350 "C18H24N2O5" @default.
- NCIT_C76135 NCIT_P366 "Enalaprilat_Anhydrous" @default.
- NCIT_C76135 NCIT_P368 "CHEBI:4786" @default.
- NCIT_C76135 normalizedInformationContent "100" @default.
- NCIT_C76135 referenceCount "1" @default.
- NCIT_C76135 hasExactSynonym "ENALAPRILAT ANHYDROUS" @default.
- NCIT_C76135 hasExactSynonym "Enalaprilat Anhydrous" @default.
- NCIT_C76135 inSubset NCIT_C63923 @default.
- NCIT_C76135 type Class @default.
- NCIT_C76135 isDefinedBy ncit.owl @default.
- NCIT_C76135 label "Enalaprilat Anhydrous" @default.
- NCIT_C76135 subClassOf NCIT_C1908 @default.
- NCIT_C76135 subClassOf NCIT_C1909 @default.
- NCIT_C76135 subClassOf NCIT_C247 @default.
- NCIT_C76135 subClassOf NCIT_C270 @default.
- NCIT_C76135 subClassOf NCIT_C471 @default.
- NCIT_C76135 subClassOf NCIT_C76135 @default.
- NCIT_C76135 subClassOf NCIT_C78274 @default.
- NCIT_C76135 subClassOf NCIT_C783 @default.