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- NCIT_C76198 IAO_0000115 "A difluorocyclopropyl quinoline. Zosuquidar binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents." @default.
- NCIT_C76198 NCIT_A5 NCIT_C2225 @default.
- NCIT_C76198 NCIT_NHC0 "C76198" @default.
- NCIT_C76198 NCIT_P106 "Organic Chemical" @default.
- NCIT_C76198 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C76198 NCIT_P108 "Zosuquidar" @default.
- NCIT_C76198 NCIT_P207 "C2700337" @default.
- NCIT_C76198 NCIT_P210 "167354-41-8" @default.
- NCIT_C76198 NCIT_P319 "AB5K82X98Y" @default.
- NCIT_C76198 NCIT_P322 "FDA" @default.
- NCIT_C76198 NCIT_P350 "C32H31F2N3O2" @default.
- NCIT_C76198 NCIT_P366 "Zosuquidar" @default.
- NCIT_C76198 normalizedInformationContent "100" @default.
- NCIT_C76198 referenceCount "1" @default.
- NCIT_C76198 hasExactSynonym "(R)-4-((1aR,6R,10bS)-1,2-Difluoro-1,1a,6,10b-tetrahydrodibenzo(a,e)cyclopropa(c)cycloheptan-6-yl)-alpha-((5-quinoloyloxy)methyl)-1-piperazineethanol" @default.
- NCIT_C76198 hasExactSynonym "ZOSUQUIDAR" @default.
- NCIT_C76198 hasExactSynonym "Zosuquidar" @default.
- NCIT_C76198 inSubset NCIT_C63923 @default.
- NCIT_C76198 type Class @default.
- NCIT_C76198 isDefinedBy ncit.owl @default.
- NCIT_C76198 label "Zosuquidar" @default.
- NCIT_C76198 subClassOf NCIT_C1744 @default.
- NCIT_C76198 subClassOf NCIT_C1908 @default.
- NCIT_C76198 subClassOf NCIT_C1909 @default.
- NCIT_C76198 subClassOf NCIT_C76198 @default.