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- NCIT_C76216 IAO_0000115 "The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.
- NCIT_C76216 NCIT_A6 NCIT_C65229 @default.
- NCIT_C76216 NCIT_NHC0 "C76216" @default.
- NCIT_C76216 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C76216 NCIT_P108 "Amdinocillin Pivoxil" @default.
- NCIT_C76216 NCIT_P207 "C0002436" @default.
- NCIT_C76216 NCIT_P210 "32886-97-8" @default.
- NCIT_C76216 NCIT_P319 "1WAM1OQ30B" @default.
- NCIT_C76216 NCIT_P322 "FDA" @default.
- NCIT_C76216 NCIT_P350 "C21H33N3O5S" @default.
- NCIT_C76216 NCIT_P366 "Amdinocillin_Pivoxil" @default.
- NCIT_C76216 NCIT_P368 "CHEBI:51210" @default.
- NCIT_C76216 normalizedInformationContent "100" @default.
- NCIT_C76216 referenceCount "1" @default.
- NCIT_C76216 hasExactSynonym "AMDINOCILLIN PIVOXIL" @default.
- NCIT_C76216 hasExactSynonym "Amdinocillin Pivoxil" @default.
- NCIT_C76216 inSubset NCIT_C63923 @default.
- NCIT_C76216 type Class @default.
- NCIT_C76216 isDefinedBy ncit.owl @default.
- NCIT_C76216 label "Amdinocillin Pivoxil" @default.
- NCIT_C76216 subClassOf NCIT_C1500 @default.
- NCIT_C76216 subClassOf NCIT_C1908 @default.
- NCIT_C76216 subClassOf NCIT_C1909 @default.
- NCIT_C76216 subClassOf NCIT_C254 @default.
- NCIT_C76216 subClassOf NCIT_C258 @default.
- NCIT_C76216 subClassOf NCIT_C260 @default.
- NCIT_C76216 subClassOf NCIT_C76216 @default.