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- NCIT_C76224 IAO_0000115 "The anhydrous form of the sodium salt of nafcillin, a narrow-spectrum beta-lactamase-resistant penicillin with antibacterial activity. Nafcillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis." @default.
- NCIT_C76224 NCIT_NHC0 "C76224" @default.
- NCIT_C76224 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C76224 NCIT_P108 "Nafcillin Sodium Anhydrous" @default.
- NCIT_C76224 NCIT_P207 "C2698426" @default.
- NCIT_C76224 NCIT_P210 "985-16-0" @default.
- NCIT_C76224 NCIT_P319 "SY07234TTS" @default.
- NCIT_C76224 NCIT_P322 "FDA" @default.
- NCIT_C76224 NCIT_P350 "C21H21N2O5S.Na" @default.
- NCIT_C76224 NCIT_P366 "Nafcillin_Sodium_Anhydrous" @default.
- NCIT_C76224 NCIT_P368 "CHEBI:7448" @default.
- NCIT_C76224 normalizedInformationContent "100" @default.
- NCIT_C76224 referenceCount "1" @default.
- NCIT_C76224 hasExactSynonym "NAFCILLIN SODIUM ANHYDROUS" @default.
- NCIT_C76224 hasExactSynonym "Nafcillin Sodium Anhydrous" @default.
- NCIT_C76224 inSubset NCIT_C63923 @default.
- NCIT_C76224 type Class @default.
- NCIT_C76224 isDefinedBy ncit.owl @default.
- NCIT_C76224 label "Nafcillin Sodium Anhydrous" @default.
- NCIT_C76224 subClassOf NCIT_C1500 @default.
- NCIT_C76224 subClassOf NCIT_C1908 @default.
- NCIT_C76224 subClassOf NCIT_C1909 @default.
- NCIT_C76224 subClassOf NCIT_C254 @default.
- NCIT_C76224 subClassOf NCIT_C258 @default.
- NCIT_C76224 subClassOf NCIT_C260 @default.
- NCIT_C76224 subClassOf NCIT_C76224 @default.