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- NCIT_C76404 IAO_0000115 "An orally bioavailable cyclopentyltriazolopyrimidine, with antiplatelet activity. Upon oral administration, ticagrelor and its major metabolite targets and reversibly binds to the platelet adenosine diphosphate (ADP) P2Y12 receptor (P2Y12R) at a site distinct from that of the endogenous agonist ADP. This blocks the platelet signaling pathway, thereby inhibiting the activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation." @default.
- NCIT_C76404 NCIT_NHC0 "C76404" @default.
- NCIT_C76404 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C76404 NCIT_P107 "Ticagrelor" @default.
- NCIT_C76404 NCIT_P108 "Ticagrelor" @default.
- NCIT_C76404 NCIT_P207 "C1999375" @default.
- NCIT_C76404 NCIT_P210 "274693-27-5" @default.
- NCIT_C76404 NCIT_P302 "Acute Coronary Syndrome" @default.
- NCIT_C76404 NCIT_P319 "GLH0314RVC" @default.
- NCIT_C76404 NCIT_P322 "CTRP" @default.
- NCIT_C76404 NCIT_P322 "FDA" @default.
- NCIT_C76404 NCIT_P350 "C23H28F2N6O4S" @default.
- NCIT_C76404 NCIT_P366 "Ticagrelor" @default.
- NCIT_C76404 normalizedInformationContent "100" @default.
- NCIT_C76404 referenceCount "1" @default.
- NCIT_C76404 hasExactSynonym "(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol" @default.
- NCIT_C76404 hasExactSynonym "AR-C126532XX" @default.
- NCIT_C76404 hasExactSynonym "AZD6140" @default.
- NCIT_C76404 hasExactSynonym "Brilinta" @default.
- NCIT_C76404 hasExactSynonym "Brilique" @default.
- NCIT_C76404 hasExactSynonym "TICAGRELOR" @default.
- NCIT_C76404 hasExactSynonym "Thioxlant-6C" @default.
- NCIT_C76404 hasExactSynonym "Ticagrelor" @default.
- NCIT_C76404 hasExactSynonym "Ticalog" @default.
- NCIT_C76404 inSubset NCIT_C116977 @default.
- NCIT_C76404 inSubset NCIT_C116978 @default.
- NCIT_C76404 inSubset NCIT_C173381 @default.
- NCIT_C76404 inSubset NCIT_C173383 @default.
- NCIT_C76404 inSubset NCIT_C63923 @default.
- NCIT_C76404 type Class @default.
- NCIT_C76404 isDefinedBy ncit.owl @default.
- NCIT_C76404 label "Ticagrelor" @default.
- NCIT_C76404 subClassOf NCIT_C1327 @default.
- NCIT_C76404 subClassOf NCIT_C1908 @default.
- NCIT_C76404 subClassOf NCIT_C190801 @default.
- NCIT_C76404 subClassOf NCIT_C1909 @default.
- NCIT_C76404 subClassOf NCIT_C76404 @default.
- NCIT_C76404 subClassOf NCIT_C78275 @default.