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Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C7643> ?p ?o ?g. }

Showing items 1 to 100 of ±197 with 100 items per page.

NCIT_C7643 IAO_0000115 "A disorder seen following cancer chemotherapy. It is the most common cause of therapy-related myelodysplastic syndromes. It typically manifests several years after initiation of single or multi-agent chemotherapy with alkylators. Mutagenic potential of alkylating agents is believed to be age and cumulative dose-dependent. Deletions in chromosomes 5 and 7 are associated with susceptibility to this disorder. Clinical signs may include fatigue, dyspnea, bruising and frequent infections. Clinical course may progress to bone marrow failure or acute myeloid leukemia that is refractory to treatment. Prognosis is dismal with survivability usually less than one year." @default.
NCIT_C7643 NCIT_A32 NCIT_C176985 @default.
NCIT_C7643 NCIT_A32 NCIT_C177621 @default.
NCIT_C7643 NCIT_NHC0 "C7643" @default.
NCIT_C7643 NCIT_P106 "Neoplastic Process" @default.
NCIT_C7643 NCIT_P108 "Alkylating Agent-Related Myelodysplastic Syndrome" @default.
NCIT_C7643 NCIT_P207 "C1332235" @default.
NCIT_C7643 NCIT_P322 "GDC" @default.
NCIT_C7643 NCIT_P363 "Malignant" @default.
NCIT_C7643 NCIT_P366 "Alkylating_Agent-Related_Myelodysplastic_Syndrome" @default.
NCIT_C7643 NCIT_P375 "9987/3" @default.
NCIT_C7643 NCIT_P375 "Therapy-related myelodysplastic syndrome, alkylating agent related" @default.
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