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- NCIT_C76756 IAO_0000115 "A synthetic psoralen, light-activated DNA and RNA crosslinking agent, with protective activity against pathogens such as bacteria, viruses, protozoa, and leukocytes. Prior to administration amotosalen is added to plasma and platelets, then in vivo this agent penetrates pathogens and targets DNA and RNA. Upon activation by ultraviolet A light, this agent is able to form interstrand DNA and RNA crosslinks and prevents replication. Inactivation of leukocytes can prevent graft versus host disease upon transfusion." @default.
- NCIT_C76756 NCIT_A5 NCIT_C72699 @default.
- NCIT_C76756 NCIT_NHC0 "C76756" @default.
- NCIT_C76756 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C76756 NCIT_P108 "Amotosalen" @default.
- NCIT_C76756 NCIT_P207 "C1136704" @default.
- NCIT_C76756 NCIT_P210 "161262-29-9" @default.
- NCIT_C76756 NCIT_P319 "K1LDZ0VBC0" @default.
- NCIT_C76756 NCIT_P322 "FDA" @default.
- NCIT_C76756 NCIT_P350 "C17H19NO4" @default.
- NCIT_C76756 NCIT_P366 "Amotosalen" @default.
- NCIT_C76756 normalizedInformationContent "100" @default.
- NCIT_C76756 referenceCount "1" @default.
- NCIT_C76756 hasExactSynonym "AMOTOSALEN" @default.
- NCIT_C76756 hasExactSynonym "Amotosalen" @default.
- NCIT_C76756 inSubset NCIT_C63923 @default.
- NCIT_C76756 type Class @default.
- NCIT_C76756 isDefinedBy ncit.owl @default.
- NCIT_C76756 label "Amotosalen" @default.
- NCIT_C76756 subClassOf NCIT_C186664 @default.
- NCIT_C76756 subClassOf NCIT_C1908 @default.
- NCIT_C76756 subClassOf NCIT_C1909 @default.
- NCIT_C76756 subClassOf NCIT_C274 @default.
- NCIT_C76756 subClassOf NCIT_C2842 @default.
- NCIT_C76756 subClassOf NCIT_C582 @default.
- NCIT_C76756 subClassOf NCIT_C76756 @default.